rs12791734

Homo sapiens
T>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0152 (4580/29962,GnomAD)
A=0113 (3313/29118,TOPMED)
A=0116 (581/5008,1000G)
A=0212 (817/3854,ALSPAC)
A=0203 (753/3708,TWINSUK)
chr11:20595465 (GRCh38.p7) (11p15.1)
AD
GWASdb2
1   publication(s)
See rs on genome
67 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 11NC_000011.10:g.20595465T>A
GRCh37.p13 chr 11NC_000011.9:g.20617011T>A
SLC6A5 RefSeqGeneNG_013086.2:g.1066T>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.990A=0.010
1000GenomesAmericanSub694T=0.880A=0.120
1000GenomesEast AsianSub1008T=0.875A=0.125
1000GenomesEuropeSub1006T=0.824A=0.176
1000GenomesGlobalStudy-wide5008T=0.884A=0.116
1000GenomesSouth AsianSub978T=0.810A=0.190
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.788A=0.212
The Genome Aggregation DatabaseAfricanSub8730T=0.966A=0.034
The Genome Aggregation DatabaseAmericanSub838T=0.880A=0.120
The Genome Aggregation DatabaseEast AsianSub1618T=0.855A=0.145
The Genome Aggregation DatabaseEuropeSub18474T=0.788A=0.211
The Genome Aggregation DatabaseGlobalStudy-wide29962T=0.847A=0.152
The Genome Aggregation DatabaseOtherSub302T=0.870A=0.130
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.886A=0.113
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.797A=0.203
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs127917340.000992alcohol dependence21314694

eQTL of rs12791734 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs12791734 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr112063830720638379E06821296
chr112063845920638509E06821448
chr112063860920638720E06821598
chr112063874820638806E06821737
chr112063830720638379E06921296
chr112063845920638509E06921448
chr112063860920638720E06921598
chr112063874820638806E06921737
chr112062216820622253E0705157
chr112062562920625931E0708618
chr112062635820626412E0709347
chr112062665120626735E0709640
chr112062676520626815E0709754
chr112062683920626904E0709828
chr112062695020627048E0709939
chr112063230220632352E07015291
chr112063860920638720E07021598
chr112063874820638806E07021737
chr112063898320639194E07021972
chr112063924120639285E07022230
chr112063936920639411E07022358
chr112063944920639499E07022438
chr112063950420639554E07022493
chr112063975020639894E07022739
chr112062053020620580E0713519
chr112062635820626412E0719347
chr112062665120626735E0719640
chr112062676520626815E0719754
chr112062683920626904E0719828
chr112062695020627048E0719939
chr112063230220632352E07115291
chr112063830720638379E07121296
chr112063845920638509E07121448
chr112063860920638720E07121598
chr112063874820638806E07121737
chr112063898320639194E07121972
chr112063924120639285E07122230
chr112063936920639411E07122358
chr112063944920639499E07122438
chr112063950420639554E07122493
chr112063975020639894E07122739
chr112063830720638379E07221296
chr112063845920638509E07221448
chr112063860920638720E07221598
chr112063936920639411E07222358
chr112063944920639499E07222438
chr112063950420639554E07222493
chr112063102720631149E07314016
chr112063830720638379E07321296
chr112063845920638509E07321448
chr112063830720638379E07421296
chr112063845920638509E07421448
chr112063860920638720E07421598
chr112063874820638806E07421737
chr112063898320639194E07421972
chr112058533120585940E081-31071
chr112058596320586148E081-30863
chr112062676520626815E0819754
chr112062683920626904E0819828
chr112062695020627048E0819939
chr112063936920639411E08122358
chr112063944920639499E08122438
chr112063950420639554E08122493
chr112063975020639894E08122739
chr112062676520626815E0829754
chr112062683920626904E0829828
chr112062695020627048E0829939