rs12798524

Homo sapiens
A>G
None
Check p-value
SNV (Single Nucleotide Variation)
G=0200 (6009/29952,GnomAD)
G=0216 (6295/29118,TOPMED)
G=0220 (1102/5008,1000G)
G=0179 (688/3854,ALSPAC)
G=0178 (659/3708,TWINSUK)
chr11:58671182 (GRCh38.p7) (11q12.1)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 11NC_000011.10:g.58671182A>G
GRCh37.p13 chr 11NC_000011.9:g.58438655A>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.789G=0.211
1000GenomesAmericanSub694A=0.730G=0.270
1000GenomesEast AsianSub1008A=0.793G=0.207
1000GenomesEuropeSub1006A=0.814G=0.186
1000GenomesGlobalStudy-wide5008A=0.780G=0.220
1000GenomesSouth AsianSub978A=0.760G=0.240
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.821G=0.179
The Genome Aggregation DatabaseAfricanSub8722A=0.791G=0.209
The Genome Aggregation DatabaseAmericanSub838A=0.740G=0.260
The Genome Aggregation DatabaseEast AsianSub1620A=0.820G=0.180
The Genome Aggregation DatabaseEuropeSub18470A=0.805G=0.194
The Genome Aggregation DatabaseGlobalStudy-wide29952A=0.799G=0.200
The Genome Aggregation DatabaseOtherSub302A=0.720G=0.280
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.783G=0.216
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.822G=0.178
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs127985240.0006alcohol dependence20201924

eQTL of rs12798524 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
Chr11:58438655LPXNENSG00000110031.8A>G1.6545e-392962Frontal_Cortex_BA9

meQTL of rs12798524 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr115838949958389539E067-49116
chr115838963258389717E067-48938
chr115838986458390141E067-48514
chr115839025758390307E067-48348
chr115839504758395837E067-42818
chr115840704058407090E067-31565
chr115840722658407272E067-31383
chr115840741258407532E067-31123
chr115840762058407707E067-30948
chr115840777558407851E067-30804
chr115840786458408367E067-30288
chr115840843658408671E067-29984
chr115844276958442819E0674114
chr115838986458390141E068-48514
chr115839504758395837E068-42818
chr115839603958396197E068-42458
chr115839701858397178E068-41477
chr115840704058407090E068-31565
chr115840722658407272E068-31383
chr115840741258407532E068-31123
chr115840762058407707E068-30948
chr115840777558407851E068-30804
chr115840786458408367E068-30288
chr115838963258389717E069-48938
chr115838986458390141E069-48514
chr115839025758390307E069-48348
chr115839504758395837E069-42818
chr115839603958396197E069-42458
chr115840741258407532E069-31123
chr115840762058407707E069-30948
chr115840777558407851E069-30804
chr115840786458408367E069-30288
chr115840843658408671E069-29984
chr115840786458408367E070-30288
chr115838986458390141E071-48514
chr115839025758390307E071-48348
chr115839450958394647E071-44008
chr115839464858394770E071-43885
chr115839504758395837E071-42818
chr115839603958396197E071-42458
chr115840672358406796E071-31859
chr115840681658406933E071-31722
chr115840704058407090E071-31565
chr115840722658407272E071-31383
chr115840741258407532E071-31123
chr115840762058407707E071-30948
chr115840777558407851E071-30804
chr115840786458408367E071-30288
chr115840843658408671E071-29984
chr115840874858409269E071-29386
chr115844296958443517E0714314
chr115839450958394647E072-44008
chr115839464858394770E072-43885
chr115839504758395837E072-42818
chr115839603958396197E072-42458
chr115840762058407707E072-30948
chr115840777558407851E072-30804
chr115840786458408367E072-30288
chr115839504758395837E073-42818
chr115840704058407090E073-31565
chr115840722658407272E073-31383
chr115840741258407532E073-31123
chr115840762058407707E073-30948
chr115840777558407851E073-30804
chr115840786458408367E073-30288
chr115840843658408671E073-29984
chr115840874858409269E073-29386
chr115839464858394770E074-43885
chr115839504758395837E074-42818
chr115839603958396197E074-42458
chr115840741258407532E074-31123
chr115840762058407707E074-30948
chr115840777558407851E074-30804
chr115840786458408367E074-30288
chr115840843658408671E074-29984