rs12800641

Organism: Homo sapiens

Alleles: G>A

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

A=0153 (4510/29326,GnomAD)
A=0219 (6380/29118,TOPMED)
A=0191 (956/5008,1000G)
A=0111 (428/3854,ALSPAC)
A=0116 (430/3708,TWINSUK)

Position: chr11:74442195 (GRCh38.p7) (11q13.4)

Phenotype: ND

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 43 Enhancers around

Promoter: 43 Promoters around

Sequence Name	Change(s)
GRCh38.p7 chr 11	NC_000011.10:g.74442195G>A
GRCh37.p13 chr 11	NC_000011.9:g.74153240G>A

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	G=0.644	A=0.356
1000Genomes	American	Sub	694	G=0.870	A=0.130
1000Genomes	East Asian	Sub	1008	G=0.947	A=0.053
1000Genomes	Europe	Sub	1006	G=0.855	A=0.145
1000Genomes	Global	Study-wide	5008	G=0.809	A=0.191
1000Genomes	South Asian	Sub	978	G=0.800	A=0.200
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	G=0.889	A=0.111
The Genome Aggregation Database	African	Sub	8328	G=0.702	A=0.298
The Genome Aggregation Database	American	Sub	832	G=0.910	A=0.090
The Genome Aggregation Database	East Asian	Sub	1604	G=0.937	A=0.063
The Genome Aggregation Database	Europe	Sub	18264	G=0.903	A=0.096
The Genome Aggregation Database	Global	Study-wide	29326	G=0.846	A=0.153
The Genome Aggregation Database	Other	Sub	298	G=0.690	A=0.310
Trans-Omics for Precision Medicine	Global	Study-wide	29118	G=0.780	A=0.219
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	G=0.884	A=0.116

PMID	Title	Author	Journal
20158304	A genomewide association study of nicotine and alcohol dependence in Australian and Dutch populations.	Lind PA	Twin Res Hum Genet

SNP ID	p-value	Traits	Study
rs12800641	4.6E-05	alcohol and nictotine co-dependence	20158304

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

There is no significant Hi-C chromatin interaction data for this SNP.

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr11	74107725	74107872	E067	-45368
chr11	74160270	74161118	E067	7030
chr11	74179155	74179320	E067	25915
chr11	74179386	74179450	E067	26146
chr11	74172880	74173566	E068	19640
chr11	74173674	74173949	E068	20434
chr11	74179155	74179320	E068	25915
chr11	74179386	74179450	E068	26146
chr11	74180086	74180165	E068	26846
chr11	74180174	74180262	E068	26934
chr11	74185755	74185814	E068	32515
chr11	74185866	74185951	E068	32626
chr11	74186136	74186190	E068	32896
chr11	74160270	74161118	E069	7030
chr11	74185866	74185951	E069	32626
chr11	74104821	74104871	E070	-48369
chr11	74105286	74105393	E070	-47847
chr11	74160270	74161118	E071	7030
chr11	74176406	74176830	E071	23166
chr11	74176844	74176918	E071	23604
chr11	74179386	74179450	E071	26146
chr11	74180086	74180165	E071	26846
chr11	74180174	74180262	E071	26934
chr11	74179155	74179320	E072	25915
chr11	74179386	74179450	E072	26146
chr11	74184838	74185693	E073	31598
chr11	74185755	74185814	E073	32515
chr11	74185866	74185951	E073	32626
chr11	74172880	74173566	E074	19640
chr11	74173674	74173949	E074	20434
chr11	74103443	74103682	E081	-49558
chr11	74103920	74103986	E081	-49254
chr11	74104200	74104250	E081	-48990
chr11	74104510	74104559	E081	-48681
chr11	74104598	74104689	E081	-48551
chr11	74104695	74104776	E081	-48464
chr11	74104821	74104871	E081	-48369
chr11	74105286	74105393	E081	-47847
chr11	74104200	74104250	E082	-48990
chr11	74104510	74104559	E082	-48681
chr11	74104598	74104689	E082	-48551
chr11	74104695	74104776	E082	-48464
chr11	74104821	74104871	E082	-48369

Chromosome	Start	End	Region	Distance(-/+:Up/Downstream)
chr11	74108134	74108329	E067	-44911
chr11	74108359	74108421	E067	-44819
chr11	74108424	74110714	E067	-42526
chr11	74177749	74179141	E067	24509
chr11	74107878	74108096	E068	-45144
chr11	74108134	74108329	E068	-44911
chr11	74108359	74108421	E068	-44819
chr11	74108424	74110714	E068	-42526
chr11	74177749	74179141	E068	24509
chr11	74107878	74108096	E069	-45144
chr11	74108134	74108329	E069	-44911
chr11	74108359	74108421	E069	-44819
chr11	74108424	74110714	E069	-42526
chr11	74177749	74179141	E069	24509
chr11	74107878	74108096	E070	-45144
chr11	74108134	74108329	E070	-44911
chr11	74108359	74108421	E070	-44819
chr11	74108424	74110714	E070	-42526
chr11	74108359	74108421	E071	-44819
chr11	74108424	74110714	E071	-42526
chr11	74177749	74179141	E071	24509
chr11	74107878	74108096	E072	-45144
chr11	74108134	74108329	E072	-44911
chr11	74108359	74108421	E072	-44819
chr11	74108424	74110714	E072	-42526
chr11	74177749	74179141	E072	24509
chr11	74107878	74108096	E073	-45144
chr11	74108134	74108329	E073	-44911
chr11	74108359	74108421	E073	-44819
chr11	74108424	74110714	E073	-42526
chr11	74177749	74179141	E073	24509
chr11	74108359	74108421	E074	-44819
chr11	74108424	74110714	E074	-42526
chr11	74177749	74179141	E074	24509
chr11	74107878	74108096	E081	-45144
chr11	74108134	74108329	E081	-44911
chr11	74108359	74108421	E081	-44819
chr11	74108424	74110714	E081	-42526
chr11	74107878	74108096	E082	-45144
chr11	74108134	74108329	E082	-44911
chr11	74108359	74108421	E082	-44819
chr11	74108424	74110714	E082	-42526
chr11	74177749	74179141	E082	24509