SNP Detail Info-rs12882384

Variant Details Frequency Publications p-values eSNP meSNP

Genomic Coordinates

Sequence Name	Change(s)
GRCh38.p7 chr 14	NC_000014.9:g.93519101A>C
GRCh38.p7 chr 14	NC_000014.9:g.93519101A>G
GRCh38.p7 chr 14 alt locus HSCHR14_7_CTG1	NT_187601.1:g.633663A>C
GRCh38.p7 chr 14 alt locus HSCHR14_7_CTG1	NT_187601.1:g.633663A>G
GRCh37.p13 chr 14	NC_000014.8:g.93985447A>C
GRCh37.p13 chr 14	NC_000014.8:g.93985447A>G

Gene: UNC79, unc-79 homolog (C. elegans)(plus strand)

Molecule type	Change	Amino acid[Codon]	SO Term
UNC79 transcript	NM_020818.3:c.	N/A	Intron Variant
UNC79 transcript variant X1	XM_011537018.2:c.	N/A	Intron Variant
UNC79 transcript variant X2	XM_011537020.2:c.	N/A	Intron Variant
UNC79 transcript variant X5	XM_011537021.2:c.	N/A	Intron Variant
UNC79 transcript variant X7	XM_011537022.2:c.	N/A	Intron Variant
UNC79 transcript variant X8	XM_011537023.2:c.	N/A	Intron Variant
UNC79 transcript variant X13	XM_011537024.2:c.	N/A	Intron Variant
UNC79 transcript variant X14	XM_011537025.2:c.	N/A	Intron Variant
UNC79 transcript variant X19	XM_011537026.2:c.	N/A	Intron Variant
UNC79 transcript variant X20	XM_011537027.2:c.	N/A	Intron Variant
UNC79 transcript variant X22	XM_011537028.2:c.	N/A	Intron Variant
UNC79 transcript variant X3	XM_017021506.1:c.	N/A	Intron Variant
UNC79 transcript variant X4	XM_017021507.1:c.	N/A	Intron Variant
UNC79 transcript variant X6	XM_017021508.1:c.	N/A	Intron Variant
UNC79 transcript variant X9	XM_017021509.1:c.	N/A	Intron Variant
UNC79 transcript variant X11	XM_017021510.1:c.	N/A	Intron Variant
UNC79 transcript variant X11	XM_017021511.1:c.	N/A	Intron Variant
UNC79 transcript variant X12	XM_017021512.1:c.	N/A	Intron Variant
UNC79 transcript variant X12	XM_017021513.1:c.	N/A	Intron Variant
UNC79 transcript variant X15	XM_017021514.1:c.	N/A	Intron Variant
UNC79 transcript variant X16	XM_017021515.1:c.	N/A	Intron Variant
UNC79 transcript variant X18	XM_017021516.1:c.	N/A	Intron Variant
UNC79 transcript variant X21	XM_017021517.1:c.	N/A	Intron Variant
UNC79 transcript variant X23	XM_017021518.1:c.	N/A	5 Prime UTR Variant
UNC79 transcript variant X25	XM_011537029.2:c.	N/A	Genic Upstream Transcript Variant
UNC79 transcript variant X24	XM_017021519.1:c.	N/A	Genic Upstream Transcript Variant
UNC79 transcript variant X26	XM_017021520.1:c.	N/A	Genic Upstream Transcript Variant

Population Frequency

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	A=0.743	G=0.257
1000Genomes	American	Sub	694	A=0.760	G=0.240
1000Genomes	East Asian	Sub	1008	A=0.303	G=0.697
1000Genomes	Europe	Sub	1006	A=0.710	G=0.290
1000Genomes	Global	Study-wide	5008	A=0.629	G=0.371
1000Genomes	South Asian	Sub	978	A=0.640	G=0.360
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	A=0.679	G=0.321
The Genome Aggregation Database	African	Sub	8708	A=0.745	G=0.255
The Genome Aggregation Database	American	Sub	834	A=0.720	G=0.280
The Genome Aggregation Database	East Asian	Sub	1610	A=0.352	G=0.648
The Genome Aggregation Database	Europe	Sub	18374	A=0.675	G=0.324
The Genome Aggregation Database	Global	Study-wide	29826	A=0.679	G=0.320
The Genome Aggregation Database	Other	Sub	300	A=0.710	G=0.290
Trans-Omics for Precision Medicine	Global	Study-wide	29118	A=0.720	G=0.279
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	A=0.685	G=0.315

PMID	Title	Author	Journal
22536871	Convergence of genetic influences in comorbidity.	McEachin RC	BMC Bioinformatics
20158304	A genomewide association study of nicotine and alcohol dependence in Australian and Dutch populations.	Lind PA	Twin Res Hum Genet
21876473	Confirmation of prior evidence of genetic susceptibility to alcoholism in a genome-wide association study of comorbid alcoholism and bipolar disorder.	Lydall GJ	Psychiatr Genet
24904279	The sodium leak channel, NALCN, in health and disease.	Cochet-Bissuel M	Front Cell Neurosci

P-Value

SNP ID	p-value	Traits	Study
rs12882384	4.86E-08	alcohol and nictotine co-dependence	20158304
rs12882384	0.0000194	Nicotine dependence (smoking)	20158304

eQTL of rs12882384 in Brain tissues (GTEx Analysis Release V7)

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

meQTL of rs12882384 in Fetal Brain

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

rs12882384

Genomic Coordinates

Gene: UNC79, unc-79 homolog (C. elegans)(plus strand)

Population Frequency

P-Value

eQTL of rs12882384 in Brain tissues (GTEx Analysis Release V7)

meQTL of rs12882384 in Fetal Brain

Genomic View

Chromatin Interaction