rs12890528

Homo sapiens
C>A / C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0094 (2808/29772,GnomAD)
T=0077 (2252/29118,TOPMED)
T=0048 (242/5008,1000G)
chr14:40935888 (GRCh38.p7) (14q21.1)
AD
GWASdb2
1   publication(s)
See rs on genome
18 Enhancers around
30 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 14NC_000014.9:g.40935888C>A
GRCh38.p7 chr 14NC_000014.9:g.40935888C>T
GRCh37.p13 chr 14NC_000014.8:g.41405093C>A
GRCh37.p13 chr 14NC_000014.8:g.41405093C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.969T=0.031
1000GenomesAmericanSub694C=0.950T=0.050
1000GenomesEast AsianSub1008C=0.999T=0.001
1000GenomesEuropeSub1006C=0.860T=0.140
1000GenomesGlobalStudy-wide5008C=0.952T=0.048
1000GenomesSouth AsianSub978C=0.970T=0.030
The Genome Aggregation DatabaseAfricanSub8680C=0.967T=0.033
The Genome Aggregation DatabaseAmericanSub830C=0.930T=0.07,
The Genome Aggregation DatabaseEast AsianSub1608C=0.999T=0.001
The Genome Aggregation DatabaseEuropeSub18354C=0.866T=0.133
The Genome Aggregation DatabaseGlobalStudy-wide29772C=0.905T=0.094
The Genome Aggregation DatabaseOtherSub300C=0.930T=0.07,
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.922T=0.077
PMID Title Author Journal
21956439Genome-wide association study of alcohol dependence implicates KIAA0040 on chromosome 1q.Zuo LNeuropsychopharmacology

P-Value

SNP ID p-value Traits Study
rs128905287E-06alcohol dependence21956439

eQTL of rs12890528 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs12890528 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr146418008464180134E067-10312
chr146419084464190894E067398
chr146419098164191204E067535
chr146419043064190484E0680
chr146419055264190602E068106
chr146419084464190894E068398
chr146415678564156976E071-33470
chr146419173064191834E0711284
chr146418220664182460E072-7986
chr146418259064182649E072-7797
chr146417902064179093E074-11353
chr146417917364179253E074-11193
chr146418220664182460E074-7986
chr146418259064182649E074-7797
chr146417217064172864E081-17582
chr146419136564191472E081919
chr146419151264191648E0811066
chr146419173064191834E0811284






Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr146419264164193074E0672195
chr146419310464193156E0672658
chr146419322864195663E0672782
chr146419264164193074E0682195
chr146419310464193156E0682658
chr146419322864195663E0682782
chr146419264164193074E0692195
chr146419310464193156E0692658
chr146419322864195663E0692782
chr146419264164193074E0702195
chr146419310464193156E0702658
chr146419322864195663E0702782
chr146419264164193074E0712195
chr146419310464193156E0712658
chr146419322864195663E0712782
chr146419264164193074E0722195
chr146419310464193156E0722658
chr146419322864195663E0722782
chr146419264164193074E0732195
chr146419310464193156E0732658
chr146419322864195663E0732782
chr146419264164193074E0742195
chr146419310464193156E0742658
chr146419322864195663E0742782
chr146419264164193074E0812195
chr146419310464193156E0812658
chr146419322864195663E0812782
chr146419264164193074E0822195
chr146419310464193156E0822658
chr146419322864195663E0822782