rs12896581

Homo sapiens
C>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0064 (1942/29912,GnomAD)
A=0082 (2387/29118,TOPMED)
A=0069 (347/5008,1000G)
A=0046 (179/3854,ALSPAC)
A=0046 (171/3708,TWINSUK)
chr14:44640950 (GRCh38.p7) (14q21.2)
AD
GWASdb2
1   publication(s)
See rs on genome
2 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 14NC_000014.9:g.44640950C>A
GRCh37.p13 chr 14NC_000014.8:g.45110153C>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.855A=0.145
1000GenomesAmericanSub694C=0.960A=0.040
1000GenomesEast AsianSub1008C=0.990A=0.010
1000GenomesEuropeSub1006C=0.948A=0.052
1000GenomesGlobalStudy-wide5008C=0.931A=0.069
1000GenomesSouth AsianSub978C=0.930A=0.070
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.954A=0.046
The Genome Aggregation DatabaseAfricanSub8720C=0.874A=0.126
The Genome Aggregation DatabaseAmericanSub830C=0.960A=0.040
The Genome Aggregation DatabaseEast AsianSub1602C=0.991A=0.009
The Genome Aggregation DatabaseEuropeSub18458C=0.958A=0.041
The Genome Aggregation DatabaseGlobalStudy-wide29912C=0.935A=0.064
The Genome Aggregation DatabaseOtherSub302C=0.940A=0.060
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.918A=0.082
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.954A=0.046
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs128965810.00057alcohol dependence20201924

eQTL of rs12896581 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs12896581 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr144512662645126734E08216473
chr144512680245127407E08216649