| Sequence Name | Change(s) |
|---|---|
| GRCh38.p7 chr 15 | NC_000015.10:g.38703290A>G |
| GRCh37.p13 chr 15 | NC_000015.9:g.38995491A>G |
| Study | Population | Group | Sample # | Ref Allele | Alt Allele |
|---|---|---|---|---|---|
| 1000Genomes | African | Sub | 1322 | A=0.856 | G=0.144 |
| 1000Genomes | American | Sub | 694 | A=0.750 | G=0.250 |
| 1000Genomes | East Asian | Sub | 1008 | A=0.968 | G=0.032 |
| 1000Genomes | Europe | Sub | 1006 | A=0.750 | G=0.250 |
| 1000Genomes | Global | Study-wide | 5008 | A=0.832 | G=0.168 |
| 1000Genomes | South Asian | Sub | 978 | A=0.800 | G=0.200 |
| The Avon Longitudinal Study of Parents and Children | PARENT AND CHILD COHORT | Study-wide | 3854 | A=0.702 | G=0.298 |
| The Genome Aggregation Database | African | Sub | 8714 | A=0.834 | G=0.166 |
| The Genome Aggregation Database | American | Sub | 834 | A=0.760 | G=0.240 |
| The Genome Aggregation Database | East Asian | Sub | 1620 | A=0.972 | G=0.028 |
| The Genome Aggregation Database | Europe | Sub | 18482 | A=0.728 | G=0.271 |
| The Genome Aggregation Database | Global | Study-wide | 29952 | A=0.772 | G=0.227 |
| The Genome Aggregation Database | Other | Sub | 302 | A=0.730 | G=0.270 |
| Trans-Omics for Precision Medicine | Global | Study-wide | 29118 | A=0.770 | G=0.229 |
| UK 10K study - Twins | TWIN COHORT | Study-wide | 3708 | A=0.705 | G=0.295 |
| PMID | Title | Author | Journal |
|---|---|---|---|
| 18711365 | Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder. | Ferreira MA | Nat Genet |
| 22212596 | Enrichment of cis-regulatory gene expression SNPs and methylation quantitative trait loci among bipolar disorder susceptibility variants. | Gamazon ER | Mol Psychiatry |
| 23871474 | A genome-wide association analysis of a broad psychosis phenotype identifies three loci for further investigation. | Bramon E | Biol Psychiatry |
| 23089632 | A genome-wide association study of alcohol-dependence symptom counts in extended pedigrees identifies C15orf53. | Wang JC | Mol Psychiatry |
| SNP ID | p-value | Traits | Study |
|---|---|---|---|
| rs12899449 | 1.26E-05 | alcohol dependence | 23089632 |
| Position (v37) | eGene | GeneID | Variant | p-value | TSS | Tissue | |
|---|---|---|---|---|---|---|---|
| There is no eQTL annotation for this SNP | |||||||
| Probe ID | Position | Gene | beta | p-value |
|---|---|---|---|---|
| cg21039679 | chr15:38989738 | C15orf53 | -0.0256202962864761 | 6.4824e-14 |
There is no significant Hi-C chromatin interaction data for this SNP.
| Chromosome | Start | End | Region | Distance ( -/+ : Up/Downstream ) |
|---|---|---|---|---|
| chr15 | 38960652 | 38961725 | E068 | -33766 |
| chr15 | 38960652 | 38961725 | E069 | -33766 |
| chr15 | 38960652 | 38961725 | E070 | -33766 |
| chr15 | 39000028 | 39001434 | E081 | 4537 |
| chr15 | 39006466 | 39007349 | E081 | 10975 |
| chr15 | 38960518 | 38960573 | E082 | -34918 |
| chr15 | 38960652 | 38961725 | E082 | -33766 |