rs12910142

Homo sapiens
G>A
SLCO3A1 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
A=0103 (3091/29954,GnomAD)
A=0091 (2653/29118,TOPMED)
A=0166 (829/5008,1000G)
A=0103 (397/3854,ALSPAC)
A=0098 (365/3708,TWINSUK)
chr15:92080273 (GRCh38.p7) (15q26.1)
ND
GWASdb2
1   publication(s)
See rs on genome
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 15NC_000015.10:g.92080273G>A
GRCh37.p13 chr 15NC_000015.9:g.92623503G>A

Gene: SLCO3A1, solute carrier organic anion transporter family member 3A1(plus strand)

Molecule type Change Amino acid[Codon] SO Term
SLCO3A1 transcript variant 2NM_001145044.1:c.N/AIntron Variant
SLCO3A1 transcript variant 1NM_013272.3:c.N/AIntron Variant
SLCO3A1 transcript variant 3NR_135775.1:n.N/AIntron Variant
SLCO3A1 transcript variant X1XM_005254889.1:c.N/AIntron Variant
SLCO3A1 transcript variant X3XM_005254891.2:c.N/AIntron Variant
SLCO3A1 transcript variant X2XM_011521456.2:c.N/AIntron Variant
SLCO3A1 transcript variant X4XR_931795.1:n.N/AIntron Variant
SLCO3A1 transcript variant X5XR_931796.2:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.944A=0.056
1000GenomesAmericanSub694G=0.930A=0.070
1000GenomesEast AsianSub1008G=0.606A=0.394
1000GenomesEuropeSub1006G=0.917A=0.083
1000GenomesGlobalStudy-wide5008G=0.834A=0.166
1000GenomesSouth AsianSub978G=0.770A=0.230
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.897A=0.103
The Genome Aggregation DatabaseAfricanSub8716G=0.925A=0.075
The Genome Aggregation DatabaseAmericanSub836G=0.950A=0.050
The Genome Aggregation DatabaseEast AsianSub1614G=0.595A=0.405
The Genome Aggregation DatabaseEuropeSub18486G=0.906A=0.093
The Genome Aggregation DatabaseGlobalStudy-wide29954G=0.896A=0.103
The Genome Aggregation DatabaseOtherSub302G=0.960A=0.040
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.908A=0.091
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.902A=0.098
PMID Title Author Journal
22377092ANAPC1 and SLCO3A1 are associated with nicotine dependence: meta-analysis of genome-wide association studies.Wang KSDrug Alcohol Depend

P-Value

SNP ID p-value Traits Study
rs129101422.2E-05nicotine dependence (smoking)22377092

eQTL of rs12910142 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs12910142 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr159257357592573700E067-49803
chr159257402292574503E067-49000
chr159257456892574700E067-48803
chr159257478292574851E067-48652
chr159257594792576010E067-47493
chr159257649092577126E067-46377
chr159257715992577234E067-46269
chr159257728392577333E067-46170
chr159257894992579035E067-44468
chr159257914392579337E067-44166
chr159257935792579569E067-43934
chr159258442592584475E067-39028
chr159258530192585518E067-37985
chr159258571192585761E067-37742
chr159258577692585833E067-37670
chr159259094092591142E067-32361
chr159259123292591393E067-32110
chr159259265892592745E067-30758
chr159259290292593127E067-30376
chr159259321192593357E067-30146
chr159259340792593470E067-30033
chr159259349692593825E067-29678
chr159259389592594090E067-29413
chr159259488092594979E067-28524
chr159259501392595226E067-28277
chr159259527892595351E067-28152
chr159259702192597140E067-26363
chr159259732992597447E067-26056
chr159260021092600439E067-23064
chr159260130592601360E067-22143
chr159260136392601489E067-22014
chr159260175392601852E067-21651
chr159260203192602145E067-21358
chr159260218192602891E067-20612
chr159260296092603489E067-20014
chr159260439192604542E067-18961
chr159260465792604759E067-18744
chr159260496192605052E067-18451
chr159260513292605252E067-18251
chr159261006892610118E067-13385
chr159261017192610221E067-13282
chr159261065292610768E067-12735
chr159261084692611026E067-12477
chr159261143392611742E067-11761
chr159261175892611831E067-11672
chr159261230392612369E067-11134
chr159261239892612629E067-10874
chr159261271692613464E067-10039
chr159261347192613853E067-9650
chr159261434292614723E067-8780
chr159261474292614971E067-8532
chr159261499892615141E067-8362
chr159261514792615355E067-8148
chr159261765892618341E067-5162
chr159261959492619674E067-3829
chr159261974992619799E067-3704
chr159261990192620042E067-3461
chr159262048192620992E067-2511
chr159262106492621155E067-2348
chr159262510792625212E0671604
chr159262522192626027E0671718
chr159263353392633583E06710030
chr159263361192633651E06710108
chr159263365592633750E06710152
chr159263378292633832E06710279
chr159263431792634707E06710814
chr159263473792634942E06711234
chr159263497592635025E06711472
chr159264057292641568E06717069
chr159264160592641655E06718102
chr159264169692641752E06718193
chr159264187492642645E06718371
chr159264272392642773E06719220
chr159264284892642937E06719345
chr159264528892645931E06721785
chr159265410592654290E06730602
chr159265437792655334E06730874
chr159265537992656091E06731876
chr159265994892660127E06736445
chr159266024792660324E06736744
chr159266040592660899E06736902
chr159266090392661015E06737400
chr159266680192666938E06743298
chr159266701092667116E06743507
chr159266719892667849E06743695
chr159266801592668165E06744512
chr159266834992668399E06744846
chr159257649092577126E068-46377
chr159257715992577234E068-46269
chr159257728392577333E068-46170
chr159258442592584475E068-39028
chr159258514892585198E068-38305
chr159258530192585518E068-37985
chr159258571192585761E068-37742
chr159258577692585833E068-37670
chr159259265892592745E068-30758
chr159259290292593127E068-30376
chr159259321192593357E068-30146
chr159259340792593470E068-30033
chr159259349692593825E068-29678
chr159259389592594090E068-29413
chr159259450792594581E068-28922
chr159259702192597140E068-26363
chr159259732992597447E068-26056
chr159260439192604542E068-18961
chr159260465792604759E068-18744
chr159260496192605052E068-18451
chr159260513292605252E068-18251
chr159260540392606212E068-17291
chr159261143392611742E068-11761
chr159261175892611831E068-11672
chr159261230392612369E068-11134
chr159261239892612629E068-10874
chr159261271692613464E068-10039
chr159261347192613853E068-9650
chr159261434292614723E068-8780
chr159261474292614971E068-8532
chr159261499892615141E068-8362
chr159261514792615355E068-8148
chr159261636292616751E068-6752
chr159261677592616865E068-6638
chr159261691892617000E068-6503
chr159262289192623116E068-387
chr159262319192623241E068-262
chr159262334492623404E068-99
chr159262510792625212E0681604
chr159262522192626027E0681718
chr159263361192633651E06810108
chr159263365592633750E06810152
chr159263378292633832E06810279
chr159263431792634707E06810814
chr159263473792634942E06811234
chr159263497592635025E06811472
chr159263502792635138E06811524
chr159263517592635237E06811672
chr159264057292641568E06817069
chr159264160592641655E06818102
chr159264169692641752E06818193
chr159264177292641825E06818269
chr159264187492642645E06818371
chr159264272392642773E06819220
chr159264284892642937E06819345
chr159264528892645931E06821785
chr159265270392653499E06829200
chr159265351092653573E06830007
chr159265410592654290E06830602
chr159265437792655334E06830874
chr159265537992656091E06831876
chr159265629292656373E06832789
chr159265673892656788E06833235
chr159265958992659847E06836086
chr159265994892660127E06836445
chr159266024792660324E06836744
chr159266040592660899E06836902
chr159266090392661015E06837400
chr159266701092667116E06843507
chr159266719892667849E06843695
chr159266801592668165E06844512
chr159266834992668399E06844846
chr159266895092669000E06845447
chr159266927292669394E06845769
chr159257357592573700E069-49803
chr159257402292574503E069-49000
chr159257456892574700E069-48803
chr159257478292574851E069-48652
chr159257511392575157E069-48346
chr159257524292575284E069-48219
chr159257552592575575E069-47928
chr159257594792576010E069-47493
chr159257649092577126E069-46377
chr159257715992577234E069-46269
chr159257728392577333E069-46170
chr159257761392577718E069-45785
chr159257894992579035E069-44468
chr159257914392579337E069-44166
chr159257935792579569E069-43934
chr159258471392584962E069-38541
chr159258514892585198E069-38305
chr159258530192585518E069-37985
chr159258571192585761E069-37742
chr159258577692585833E069-37670
chr159258603992586096E069-37407
chr159259123292591393E069-32110
chr159259140092591470E069-32033
chr159259149692591550E069-31953
chr159259163792591752E069-31751
chr159259211392592334E069-31169
chr159259245592592505E069-30998
chr159259265892592745E069-30758
chr159259290292593127E069-30376
chr159259321192593357E069-30146
chr159259340792593470E069-30033
chr159259349692593825E069-29678
chr159259389592594090E069-29413
chr159259450792594581E069-28922
chr159259488092594979E069-28524
chr159259501392595226E069-28277
chr159259527892595351E069-28152
chr159259702192597140E069-26363
chr159259732992597447E069-26056
chr159259932592599438E069-24065
chr159259948492599547E069-23956
chr159260021092600439E069-23064
chr159260130592601360E069-22143
chr159260136392601489E069-22014
chr159260175392601852E069-21651
chr159260203192602145E069-21358
chr159260218192602891E069-20612
chr159260423792604301E069-19202
chr159260439192604542E069-18961
chr159260465792604759E069-18744
chr159260496192605052E069-18451
chr159260513292605252E069-18251
chr159260540392606212E069-17291
chr159260977792609824E069-13679
chr159261006892610118E069-13385
chr159261017192610221E069-13282
chr159261065292610768E069-12735
chr159261084692611026E069-12477
chr159261143392611742E069-11761
chr159261175892611831E069-11672
chr159261230392612369E069-11134
chr159261239892612629E069-10874
chr159261271692613464E069-10039
chr159261347192613853E069-9650
chr159261434292614723E069-8780
chr159261474292614971E069-8532
chr159261499892615141E069-8362
chr159261514792615355E069-8148
chr159261587592615925E069-7578
chr159261702192617077E069-6426
chr159261734092617413E069-6090
chr159261746992617657E069-5846
chr159261765892618341E069-5162
chr159261838592618533E069-4970
chr159261857792618657E069-4846
chr159261877192618871E069-4632
chr159261893792619443E069-4060
chr159261959492619674E069-3829
chr159261974992619799E069-3704
chr159261990192620042E069-3461
chr159262019892620307E069-3196
chr159262032992620454E069-3049
chr159262048192620992E069-2511
chr159262106492621155E069-2348
chr159262289192623116E069-387
chr159262319192623241E069-262
chr159262334492623404E069-99
chr159262383592623941E069332
chr159262399692624046E069493
chr159262510792625212E0691604
chr159262522192626027E0691718
chr159263317192633232E0699668
chr159263330892633393E0699805
chr159263353392633583E06910030
chr159263361192633651E06910108
chr159263365592633750E06910152
chr159263378292633832E06910279
chr159263473792634942E06911234
chr159263497592635025E06911472
chr159263502792635138E06911524
chr159263517592635237E06911672
chr159263647292636711E06912969
chr159264057292641568E06917069
chr159264160592641655E06918102
chr159264169692641752E06918193
chr159264177292641825E06918269
chr159264497092645260E06921467
chr159264528892645931E06921785
chr159264636092646454E06922857
chr159264657792646654E06923074
chr159264680992646863E06923306
chr159265242792652661E06928924
chr159265270392653499E06929200
chr159265351092653573E06930007
chr159265410592654290E06930602
chr159265437792655334E06930874
chr159265537992656091E06931876
chr159265629292656373E06932789
chr159265673892656788E06933235
chr159265923492659355E06935731
chr159265958992659847E06936086
chr159265994892660127E06936445
chr159266024792660324E06936744
chr159266040592660899E06936902
chr159266090392661015E06937400
chr159266680192666938E06943298
chr159266701092667116E06943507
chr159266719892667849E06943695
chr159266801592668165E06944512
chr159266834992668399E06944846
chr159266895092669000E06945447
chr159266927292669394E06945769
chr159266961192669696E06946108
chr159262510792625212E0701604
chr159262522192626027E0701718
chr159264057292641568E07017069
chr159264702492647078E07023521
chr159264718592647416E07023682
chr159266090392661015E07037400
chr159266128892661338E07037785
chr159266146192661738E07037958
chr159266180492662053E07038301
chr159266801592668165E07044512
chr159267018192670231E07046678
chr159257357592573700E071-49803
chr159257402292574503E071-49000
chr159257456892574700E071-48803
chr159257478292574851E071-48652
chr159257511392575157E071-48346
chr159257524292575284E071-48219
chr159257552592575575E071-47928
chr159257594792576010E071-47493
chr159257649092577126E071-46377
chr159257715992577234E071-46269
chr159257728392577333E071-46170
chr159257761392577718E071-45785
chr159258471392584962E071-38541
chr159258514892585198E071-38305
chr159258530192585518E071-37985
chr159259140092591470E071-32033
chr159259149692591550E071-31953
chr159259163792591752E071-31751
chr159259211392592334E071-31169
chr159259245592592505E071-30998
chr159259265892592745E071-30758
chr159259290292593127E071-30376
chr159259321192593357E071-30146
chr159259340792593470E071-30033
chr159259349692593825E071-29678
chr159259389592594090E071-29413
chr159259450792594581E071-28922
chr159259488092594979E071-28524
chr159259501392595226E071-28277
chr159259527892595351E071-28152
chr159259732992597447E071-26056
chr159259770592597791E071-25712
chr159259932592599438E071-24065
chr159259948492599547E071-23956
chr159260021092600439E071-23064
chr159260130592601360E071-22143
chr159260136392601489E071-22014
chr159260175392601852E071-21651
chr159260203192602145E071-21358
chr159260218192602891E071-20612
chr159260296092603489E071-20014
chr159260439192604542E071-18961
chr159260465792604759E071-18744
chr159260496192605052E071-18451
chr159260513292605252E071-18251
chr159260540392606212E071-17291
chr159261065292610768E071-12735
chr159261084692611026E071-12477
chr159261143392611742E071-11761
chr159261175892611831E071-11672
chr159261230392612369E071-11134
chr159261239892612629E071-10874
chr159261271692613464E071-10039
chr159261347192613853E071-9650
chr159261434292614723E071-8780
chr159261474292614971E071-8532
chr159261499892615141E071-8362
chr159261514792615355E071-8148
chr159261587592615925E071-7578
chr159261636292616751E071-6752
chr159261677592616865E071-6638
chr159261691892617000E071-6503
chr159261702192617077E071-6426
chr159261734092617413E071-6090
chr159261746992617657E071-5846
chr159261765892618341E071-5162
chr159261838592618533E071-4970
chr159261857792618657E071-4846
chr159261877192618871E071-4632
chr159261893792619443E071-4060
chr159261959492619674E071-3829
chr159261974992619799E071-3704
chr159261990192620042E071-3461
chr159262019892620307E071-3196
chr159262032992620454E071-3049
chr159262048192620992E071-2511
chr159262106492621155E071-2348
chr159262239692622596E071-907
chr159262266992622726E071-777
chr159262289192623116E071-387
chr159262319192623241E071-262
chr159262334492623404E071-99
chr159262510792625212E0711604
chr159262522192626027E0711718
chr159263317192633232E0719668
chr159263330892633393E0719805
chr159263353392633583E07110030
chr159263361192633651E07110108
chr159263365592633750E07110152
chr159263378292633832E07110279
chr159263431792634707E07110814
chr159263473792634942E07111234
chr159263497592635025E07111472
chr159263502792635138E07111524
chr159263517592635237E07111672
chr159263647292636711E07112969
chr159264057292641568E07117069
chr159264160592641655E07118102
chr159264169692641752E07118193
chr159264177292641825E07118269
chr159264187492642645E07118371
chr159264272392642773E07119220
chr159264528892645931E07121785
chr159264680992646863E07123306
chr159265147992651643E07127976
chr159265168592651802E07128182
chr159265184992652056E07128346
chr159265209792652255E07128594
chr159265242792652661E07128924
chr159265270392653499E07129200
chr159265351092653573E07130007
chr159265410592654290E07130602
chr159265437792655334E07130874
chr159265537992656091E07131876
chr159265629292656373E07132789
chr159265673892656788E07133235
chr159265682492656980E07133321
chr159265958992659847E07136086
chr159265994892660127E07136445
chr159266024792660324E07136744
chr159266040592660899E07136902
chr159266090392661015E07137400
chr159266128892661338E07137785
chr159266146192661738E07137958
chr159266180492662053E07138301
chr159266680192666938E07143298
chr159266701092667116E07143507
chr159266719892667849E07143695
chr159266801592668165E07144512
chr159266834992668399E07144846
chr159266895092669000E07145447
chr159257402292574503E072-49000
chr159257456892574700E072-48803
chr159257478292574851E072-48652
chr159257511392575157E072-48346
chr159257524292575284E072-48219
chr159257552592575575E072-47928
chr159257594792576010E072-47493
chr159257649092577126E072-46377
chr159257715992577234E072-46269
chr159257728392577333E072-46170
chr159257761392577718E072-45785
chr159257805292578134E072-45369
chr159257875292578835E072-44668
chr159257894992579035E072-44468
chr159257914392579337E072-44166
chr159257935792579569E072-43934
chr159258419592584245E072-39258
chr159258425492584304E072-39199
chr159258442592584475E072-39028
chr159258471392584962E072-38541
chr159258514892585198E072-38305
chr159258530192585518E072-37985
chr159258571192585761E072-37742
chr159258577692585833E072-37670
chr159258603992586096E072-37407
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