rs1296438

Homo sapiens
A>C / A>G
None
Check p-value
SNV (Single Nucleotide Variation)
G=0398 (11904/29894,GnomAD)
G=0451 (13132/29118,TOPMED)
G=0469 (2347/5008,1000G)
G=0260 (1002/3854,ALSPAC)
G=0267 (991/3708,TWINSUK)
chr1:53471504 (GRCh38.p7) (1p32.3)
ND
GWASdb2
1   publication(s)
See rs on genome
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 1NC_000001.11:g.53471504A>C
GRCh38.p7 chr 1NC_000001.11:g.53471504A>G
GRCh37.p13 chr 1NC_000001.10:g.53937177A>C
GRCh37.p13 chr 1NC_000001.10:g.53937177A>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.258G=0.742
1000GenomesAmericanSub694A=0.780G=0.220
1000GenomesEast AsianSub1008A=0.468G=0.532
1000GenomesEuropeSub1006A=0.724G=0.276
1000GenomesGlobalStudy-wide5008A=0.531G=0.469
1000GenomesSouth AsianSub978A=0.590G=0.410
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.740G=0.260
The Genome Aggregation DatabaseAfricanSub8706A=0.306C=0.000
The Genome Aggregation DatabaseAmericanSub836A=0.820C=0.00,
The Genome Aggregation DatabaseEast AsianSub1616A=0.502C=0.000
The Genome Aggregation DatabaseEuropeSub18436A=0.738C=0.000
The Genome Aggregation DatabaseGlobalStudy-wide29894A=0.601C=0.000
The Genome Aggregation DatabaseOtherSub300A=0.660C=0.00,
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.549G=0.451
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.733G=0.267
PMID Title Author Journal
23942779A genome-wide association study of behavioral disinhibition.McGue MBehav Genet

P-Value

SNP ID p-value Traits Study
rs12964387.9E-06nicotine use23942779

eQTL of rs1296438 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1296438 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr15388265653883206E067-29874
chr15393622653936439E06723146
chr15393645953936605E06723379
chr15388265653883206E068-29874
chr15393622653936439E06823146
chr15393645953936605E06823379
chr15388265653883206E069-29874
chr15388352353883596E069-29484
chr15388375653883816E069-29264
chr15387526753875401E070-37679
chr15387559153875727E070-37353
chr15387585353875999E070-37081
chr15387613853876270E070-36810
chr15387646453876604E070-36476
chr15387873953879534E070-33546
chr15387987953879967E070-33113
chr15388009353880218E070-32862
chr15388106253881221E070-31859
chr15388145653881552E070-31528
chr15388164753882517E070-30563
chr15388375653883816E070-29264
chr15388480353884961E070-28119
chr15388653353886625E070-26455
chr15388678353886851E070-26229
chr15389630153896863E070-16217
chr15389722353897344E070-15736
chr15392849853928758E07015418
chr15393579353936205E07022713
chr15394054753940640E07027467
chr15394065753940733E07027577
chr15388265653883206E071-29874
chr15388352353883596E071-29484
chr15393579353936205E07122713
chr15393622653936439E07123146
chr15393645953936605E07123379
chr15395162853951782E07138548
chr15387987953879967E072-33113
chr15388265653883206E072-29874
chr15393622653936439E07223146
chr15393645953936605E07223379
chr15394335153943448E07230271
chr15394369353943762E07230613
chr15395116253951586E07238082
chr15393579353936205E07322713
chr15393622653936439E07323146
chr15393645953936605E07323379
chr15388265653883206E074-29874
chr15393645953936605E07423379
chr15387479053874844E081-38236
chr15387526753875401E081-37679
chr15387559153875727E081-37353
chr15387585353875999E081-37081
chr15387613853876270E081-36810
chr15387873953879534E081-33546
chr15387987953879967E081-33113
chr15388009353880218E081-32862
chr15388106253881221E081-31859
chr15388145653881552E081-31528
chr15388164753882517E081-30563
chr15388265653883206E081-29874
chr15388352353883596E081-29484
chr15388375653883816E081-29264
chr15388480353884961E081-28119
chr15389596353896272E081-16808
chr15389630153896863E081-16217
chr15392070553920807E0817625
chr15392849853928758E08115418
chr15392988153930081E08116801
chr15393083553931032E08117755
chr15395116253951586E08138082
chr15395162853951782E08138548
chr15387479053874844E082-38236
chr15387646453876604E082-36476
chr15387873953879534E082-33546
chr15387987953879967E082-33113
chr15388009353880218E082-32862
chr15388106253881221E082-31859
chr15388145653881552E082-31528
chr15388164753882517E082-30563
chr15388352353883596E082-29484
chr15388375653883816E082-29264
chr15388480353884961E082-28119
chr15389596353896272E082-16808
chr15389630153896863E082-16217
chr15389722353897344E082-15736
chr15392070553920807E0827625
chr15392849853928758E08215418
chr15392988153930081E08216801
chr15394413853944497E08231058
chr15394591653945966E08232836