rs1298637

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0448 (13439/29944,GnomAD)
C==0474 (13825/29118,TOPMED)
C==0469 (2347/5008,1000G)
T=0259 (999/3854,ALSPAC)
T=0265 (984/3708,TWINSUK)
chr1:53492930 (GRCh38.p7) (1p32.3)
ND
GWASdb2 | GWASCatalog
1   publication(s)
See rs on genome
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 1NC_000001.11:g.53492930C>T
GRCh37.p13 chr 1NC_000001.10:g.53958603C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.050T=0.950
1000GenomesAmericanSub694C=0.760T=0.240
1000GenomesEast AsianSub1008C=0.487T=0.513
1000GenomesEuropeSub1006C=0.722T=0.278
1000GenomesGlobalStudy-wide5008C=0.469T=0.531
1000GenomesSouth AsianSub978C=0.550T=0.450
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.741T=0.259
The Genome Aggregation DatabaseAfricanSub8720C=0.136T=0.864
The Genome Aggregation DatabaseAmericanSub836C=0.800T=0.200
The Genome Aggregation DatabaseEast AsianSub1612C=0.518T=0.482
The Genome Aggregation DatabaseEuropeSub18474C=0.736T=0.263
The Genome Aggregation DatabaseGlobalStudy-wide29944C=0.551T=0.448
The Genome Aggregation DatabaseOtherSub302C=0.660T=0.340
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.474T=0.525
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.735T=0.265
PMID Title Author Journal
23942779A genome-wide association study of behavioral disinhibition.McGue MBehav Genet

P-Value

SNP ID p-value Traits Study
rs12986375E-06nicotine use23942779

eQTL of rs1298637 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1298637 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr15393622653936439E067-22164
chr15393645953936605E067-21998
chr15398961453989664E06731011
chr15399044653990998E06731843
chr15393622653936439E068-22164
chr15393645953936605E068-21998
chr15398763353988067E06929030
chr15399044653990998E06931843
chr15392849853928758E070-29845
chr15393579353936205E070-22398
chr15394054753940640E070-17963
chr15394065753940733E070-17870
chr15396454653964722E0705943
chr15396599053966135E0707387
chr15396647353966670E0707870
chr15396901553969068E07010412
chr15396910753969861E07010504
chr15396991453970003E07011311
chr15397958053979851E07020977
chr15398011153980184E07021508
chr15398736653987442E07028763
chr15398763353988067E07029030
chr15398808353988176E07029480
chr15393579353936205E071-22398
chr15393622653936439E071-22164
chr15393645953936605E071-21998
chr15395162853951782E071-6821
chr15399044653990998E07131843
chr15393622653936439E072-22164
chr15393645953936605E072-21998
chr15394335153943448E072-15155
chr15394369353943762E072-14841
chr15395116253951586E072-7017
chr15398896853989008E07230365
chr15398909853989168E07230495
chr15398961453989664E07231011
chr15399044653990998E07231843
chr15400724754007415E07248644
chr15400750754008377E07248904
chr15393579353936205E073-22398
chr15393622653936439E073-22164
chr15393645953936605E073-21998
chr15397741353977468E07318810
chr15397748553977620E07318882
chr15399044653990998E07331843
chr15399182553991896E07333222
chr15393645953936605E074-21998
chr15398961453989664E07431011
chr15399044653990998E07431843
chr15392070553920807E081-37796
chr15392849853928758E081-29845
chr15392988153930081E081-28522
chr15393083553931032E081-27571
chr15395116253951586E081-7017
chr15395162853951782E081-6821
chr15396686353967098E0818260
chr15396736453967617E0818761
chr15396901553969068E08110412
chr15396910753969861E08110504
chr15397958053979851E08120977
chr15398736653987442E08128763
chr15398763353988067E08129030
chr15398808353988176E08129480
chr15399222053992822E08133617
chr15400160654001888E08143003
chr15392070553920807E082-37796
chr15392849853928758E082-29845
chr15392988153930081E082-28522
chr15394413853944497E082-14106
chr15394591653945966E082-12637
chr15396901553969068E08210412
chr15396910753969861E08210504
chr15397903853979177E08220435
chr15397958053979851E08220977
chr15400145054001542E08242847
chr15400160654001888E08243003