rs13106651

Homo sapiens
A>G
SEPSECS-AS1 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
A==0359 (10766/29930,GnomAD)
A==0398 (11614/29118,TOPMED)
A==0414 (2075/5008,1000G)
A==0309 (1191/3854,ALSPAC)
A==0313 (1161/3708,TWINSUK)
chr4:25181823 (GRCh38.p7) (4p15.2)
AD
GWASdb2
1   publication(s)
See rs on genome
23 Enhancers around
15 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 4NC_000004.12:g.25181823A>G
GRCh37.p13 chr 4NC_000004.11:g.25183445A>G

Gene: SEPSECS-AS1, SEPSECS antisense RNA 1 (head to head)(plus strand)

Molecule type Change Amino acid[Codon] SO Term
SEPSECS-AS1 transcriptNR_037934.1:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.529G=0.471
1000GenomesAmericanSub694A=0.370G=0.630
1000GenomesEast AsianSub1008A=0.459G=0.541
1000GenomesEuropeSub1006A=0.342G=0.658
1000GenomesGlobalStudy-wide5008A=0.414G=0.586
1000GenomesSouth AsianSub978A=0.320G=0.680
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.309G=0.691
The Genome Aggregation DatabaseAfricanSub8702A=0.496G=0.504
The Genome Aggregation DatabaseAmericanSub838A=0.330G=0.670
The Genome Aggregation DatabaseEast AsianSub1610A=0.429G=0.571
The Genome Aggregation DatabaseEuropeSub18478A=0.292G=0.708
The Genome Aggregation DatabaseGlobalStudy-wide29930A=0.359G=0.640
The Genome Aggregation DatabaseOtherSub302A=0.300G=0.700
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.398G=0.601
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.313G=0.687
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs131066510.000383alcohol dependence21314694

eQTL of rs13106651 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs13106651 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr42516373025163780E067-19665
chr42516381225163862E067-19583
chr42516392525163975E067-19470
chr42517446725175702E067-7743
chr42517640825176621E067-6824
chr42516373025163780E068-19665
chr42516381225163862E068-19583
chr42516392525163975E068-19470
chr42516373025163780E069-19665
chr42517446725175702E069-7743
chr42516373025163780E071-19665
chr42516381225163862E071-19583
chr42516392525163975E071-19470
chr42517446725175702E071-7743
chr42516373025163780E072-19665
chr42516381225163862E072-19583
chr42516392525163975E072-19470
chr42516522625165280E072-18165
chr42517446725175702E072-7743
chr42516373025163780E073-19665
chr42516381225163862E073-19583
chr42516392525163975E073-19470
chr42516373025163780E074-19665







Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr42516085825161178E067-22267
chr42516131725163565E067-19880
chr42516131725163565E068-19880
chr42516131725163565E069-19880
chr42516085825161178E070-22267
chr42516131725163565E070-19880
chr42516085825161178E071-22267
chr42516131725163565E071-19880
chr42516131725163565E072-19880
chr42516085825161178E073-22267
chr42516131725163565E073-19880
chr42516085825161178E074-22267
chr42516131725163565E074-19880
chr42516085825161178E082-22267
chr42516131725163565E082-19880