rs13170785

Homo sapiens
G>A
ARL10 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
G==0412 (11033/26740,GnomAD)
G==0449 (2247/5008,1000G)
G==0386 (1486/3854,ALSPAC)
G==0391 (1449/3708,TWINSUK)
chr5:176368663 (GRCh38.p7) (5q35.2)
AD
GWASdb2
1   publication(s)
See rs on genome
85 Enhancers around
39 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 5NC_000005.10:g.176368663G>A
GRCh37.p13 chr 5NC_000005.9:g.175795666G>A

Gene: ARL10, ADP ribosylation factor like GTPase 10(plus strand)

Molecule type Change Amino acid[Codon] SO Term
ARL10 transcript variant 1NM_001317948.1:c.N/AIntron Variant
ARL10 transcript variant 2NM_173664.5:c.N/AIntron Variant
ARL10 transcript variant X1XM_011534529.2:c.N/AIntron Variant
ARL10 transcript variant X2XM_011534530.2:c.N/AIntron Variant
ARL10 transcript variant X3XM_011534531.2:c.N/AIntron Variant
ARL10 transcript variant X4XM_017009372.1:c.N/AGenic Downstream Transcript Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.424A=0.576
1000GenomesAmericanSub694G=0.510A=0.490
1000GenomesEast AsianSub1008G=0.445A=0.555
1000GenomesEuropeSub1006G=0.393A=0.607
1000GenomesGlobalStudy-wide5008G=0.449A=0.551
1000GenomesSouth AsianSub978G=0.500A=0.500
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.386A=0.614
The Genome Aggregation DatabaseAfricanSub7816G=0.425A=0.575
The Genome Aggregation DatabaseAmericanSub780G=0.500A=0.500
The Genome Aggregation DatabaseEast AsianSub1448G=0.442A=0.558
The Genome Aggregation DatabaseEuropeSub16428G=0.400A=0.599
The Genome Aggregation DatabaseGlobalStudy-wide26740G=0.412A=0.587
The Genome Aggregation DatabaseOtherSub268G=0.360A=0.640
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.391A=0.609
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs131707850.000584alcohol dependence20201924

eQTL of rs13170785 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs13170785 in Fetal Brain

Probe ID Position Gene beta p-value
cg26620356chr5:175789238KIAA1191-0.06756749858025566.7653e-15
cg05970307chr5:175789566KIAA1191-0.04736002376133162.0391e-13

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr5175789718175789874E067-5792
chr5175813882175813929E06718216
chr5175838098175838218E06742432
chr5175838284175838430E06742618
chr5175838478175838614E06742812
chr5175839468175839608E06743802
chr5175839735175839853E06744069
chr5175839872175839922E06744206
chr5175840010175840095E06744344
chr5175840163175840554E06744497
chr5175840666175840719E06745000
chr5175840748175840870E06745082
chr5175840940175841022E06745274
chr5175841314175841367E06745648
chr5175782512175782653E068-13013
chr5175782705175782798E068-12868
chr5175782846175782955E068-12711
chr5175783053175783244E068-12422
chr5175840666175840719E06845000
chr5175840748175840870E06845082
chr5175840940175841022E06845274
chr5175841314175841367E06845648
chr5175841670175841724E06846004
chr5175841753175841823E06846087
chr5175783053175783244E069-12422
chr5175839468175839608E06943802
chr5175839735175839853E06944069
chr5175839872175839922E06944206
chr5175840010175840095E06944344
chr5175840163175840554E06944497
chr5175840666175840719E06945000
chr5175840748175840870E06945082
chr5175783053175783244E070-12422
chr5175786741175787026E070-8640
chr5175813882175813929E07018216
chr5175786741175787026E071-8640
chr5175787427175787467E071-8199
chr5175840010175840095E07144344
chr5175840163175840554E07144497
chr5175840666175840719E07145000
chr5175840748175840870E07145082
chr5175841753175841823E07146087
chr5175786741175787026E072-8640
chr5175828416175828544E07232750
chr5175840163175840554E07244497
chr5175840666175840719E07245000
chr5175840748175840870E07245082
chr5175784607175784666E073-11000
chr5175823617175823852E07327951
chr5175823938175824032E07328272
chr5175824121175824350E07328455
chr5175839735175839853E07344069
chr5175839872175839922E07344206
chr5175840010175840095E07344344
chr5175840163175840554E07344497
chr5175841314175841367E07345648
chr5175782846175782955E074-12711
chr5175783053175783244E074-12422
chr5175786741175787026E074-8640
chr5175839468175839608E07443802
chr5175839735175839853E07444069
chr5175839872175839922E07444206
chr5175786741175787026E081-8640
chr5175787427175787467E081-8199
chr5175789718175789874E081-5792
chr5175813882175813929E08118216
chr5175840940175841022E08145274
chr5175841314175841367E08145648
chr5175841670175841724E08146004
chr5175841753175841823E08146087
chr5175784607175784666E082-11000
chr5175794869175794940E082-726
chr5175813882175813929E08218216
chr5175838098175838218E08242432
chr5175838284175838430E08242618
chr5175838478175838614E08242812
chr5175839468175839608E08243802
chr5175839735175839853E08244069
chr5175839872175839922E08244206
chr5175840010175840095E08244344
chr5175840163175840554E08244497
chr5175840940175841022E08245274
chr5175841314175841367E08245648
chr5175841670175841724E08246004
chr5175841753175841823E08246087










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr5175787898175789634E067-6032
chr5175791943175793683E067-1983
chr5175814655175814868E06718989
chr5175814935175816695E06719269
chr5175787898175789634E068-6032
chr5175791943175793683E068-1983
chr5175814655175814868E06818989
chr5175814935175816695E06819269
chr5175787898175789634E069-6032
chr5175791943175793683E069-1983
chr5175814655175814868E06918989
chr5175814935175816695E06919269
chr5175787898175789634E070-6032
chr5175791943175793683E070-1983
chr5175814655175814868E07018989
chr5175814935175816695E07019269
chr5175787898175789634E071-6032
chr5175791943175793683E071-1983
chr5175814655175814868E07118989
chr5175814935175816695E07119269
chr5175787898175789634E072-6032
chr5175791943175793683E072-1983
chr5175814655175814868E07218989
chr5175814935175816695E07219269
chr5175787898175789634E073-6032
chr5175791943175793683E073-1983
chr5175814655175814868E07318989
chr5175814935175816695E07319269
chr5175787898175789634E074-6032
chr5175791943175793683E074-1983
chr5175814655175814868E07418989
chr5175814935175816695E07419269
chr5175787898175789634E081-6032
chr5175814655175814868E08118989
chr5175814935175816695E08119269
chr5175787898175789634E082-6032
chr5175791943175793683E082-1983
chr5175814655175814868E08218989
chr5175814935175816695E08219269