rs13197942

Homo sapiens
G>T
IYD : 500B Downstream Variant
Check p-value
SNV (Single Nucleotide Variation)
T=0086 (2590/29980,GnomAD)
T=0102 (2972/29118,TOPMED)
T=0080 (400/5008,1000G)
T=0119 (459/3854,ALSPAC)
T=0116 (431/3708,TWINSUK)
chr6:150404961 (GRCh38.p7) (6q25.1)
AD
GWASdb2
1   publication(s)
See rs on genome
21 Enhancers around
6 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 6NC_000006.12:g.150404961G>T
GRCh37.p13 chr 6NC_000006.11:g.150726097G>T
IYD RefSeqGeneNG_016007.1:g.41070G>T

Gene: IYD, iodotyrosine deiodinase(plus strand): 500B Downstream Variant

Molecule type Change Amino acid[Codon] SO Term
IYD transcript variant 1NM_001164694.1:c.N/ADownstream Transcript Variant
IYD transcript variant 3NM_001164695.1:c.N/ADownstream Transcript Variant
IYD transcript variant 4NM_001318495.1:c.N/ADownstream Transcript Variant
IYD transcript variant 2NM_203395.2:c.N/ADownstream Transcript Variant
IYD transcript variant 5NR_134655.1:n.N/ADownstream Transcript Variant
IYD transcript variant X1XM_006715478.3:c.N/AN/A
IYD transcript variant X2XM_006715479.3:c.N/AN/A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.916T=0.084
1000GenomesAmericanSub694G=0.920T=0.080
1000GenomesEast AsianSub1008G=0.975T=0.025
1000GenomesEuropeSub1006G=0.901T=0.099
1000GenomesGlobalStudy-wide5008G=0.920T=0.080
1000GenomesSouth AsianSub978G=0.890T=0.110
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.881T=0.119
The Genome Aggregation DatabaseAfricanSub8718G=0.897T=0.103
The Genome Aggregation DatabaseAmericanSub834G=0.940T=0.060
The Genome Aggregation DatabaseEast AsianSub1622G=0.973T=0.027
The Genome Aggregation DatabaseEuropeSub18504G=0.914T=0.085
The Genome Aggregation DatabaseGlobalStudy-wide29980G=0.913T=0.086
The Genome Aggregation DatabaseOtherSub302G=0.940T=0.060
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.897T=0.102
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.884T=0.116
PMID Title Author Journal
23953852Genome-wide association studies of maximum number of drinks.Pan YJ Psychiatr Res

P-Value

SNP ID p-value Traits Study
rs131979421.34E-06alcohol consumption23953852

eQTL of rs13197942 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs13197942 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr6150694241150694869E067-31228
chr6150730519150731319E0674422
chr6150698101150699186E068-26911
chr6150693986150694056E069-32041
chr6150694241150694869E069-31228
chr6150694983150695037E069-31060
chr6150698101150699186E069-26911
chr6150693986150694056E070-32041
chr6150694241150694869E070-31228
chr6150730519150731319E0704422
chr6150731330150731484E0705233
chr6150731521150731572E0705424
chr6150731581150732327E0705484
chr6150733837150733940E0707740
chr6150693986150694056E071-32041
chr6150698101150699186E071-26911
chr6150699197150699282E071-26815
chr6150693313150693445E073-32652
chr6150698101150699186E073-26911
chr6150698101150699186E074-26911
chr6150693986150694056E081-32041








Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr6150738975150740786E06812878
chr6150738975150740786E06912878
chr6150738975150740786E07112878
chr6150738975150740786E07212878
chr6150738975150740786E07312878
chr6150738975150740786E07412878