rs1321313

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0219 (6569/29938,GnomAD)
T=0219 (6393/29118,TOPMED)
T=0216 (1083/5008,1000G)
T=0235 (907/3854,ALSPAC)
T=0238 (883/3708,TWINSUK)
chr6:36651044 (GRCh38.p7) (6p21.2)
AD
GWASdb2
1   publication(s)
See rs on genome
211 Enhancers around
11 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 6NC_000006.12:g.36651044C>T
GRCh37.p13 chr 6NC_000006.11:g.36618821C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.790T=0.210
1000GenomesAmericanSub694C=0.830T=0.170
1000GenomesEast AsianSub1008C=0.832T=0.168
1000GenomesEuropeSub1006C=0.795T=0.205
1000GenomesGlobalStudy-wide5008C=0.784T=0.216
1000GenomesSouth AsianSub978C=0.680T=0.320
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.765T=0.235
The Genome Aggregation DatabaseAfricanSub8710C=0.784T=0.216
The Genome Aggregation DatabaseAmericanSub838C=0.840T=0.160
The Genome Aggregation DatabaseEast AsianSub1614C=0.827T=0.173
The Genome Aggregation DatabaseEuropeSub18474C=0.773T=0.226
The Genome Aggregation DatabaseGlobalStudy-wide29938C=0.780T=0.219
The Genome Aggregation DatabaseOtherSub302C=0.700T=0.300
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.780T=0.219
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.762T=0.238
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs13213130.00046alcohol dependence(early age of onset)20201924
rs13213130.00064alcohol dependence20201924

eQTL of rs1321313 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1321313 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr63657235136572436E067-46385
chr63657253836572695E067-46126
chr63657272436572801E067-46020
chr63657297636573042E067-45779
chr63657318136573365E067-45456
chr63657351736573763E067-45058
chr63657532136576117E067-42704
chr63658464936585367E067-33454
chr63659087836591641E067-27180
chr63659275536593308E067-25513
chr63659334736593599E067-25222
chr63660453336604803E067-14018
chr63660488636605053E067-13768
chr63663418336634271E06715362
chr63663445536634547E06715634
chr63663463736635354E06715816
chr63664388736644663E06725066
chr63664484436645401E06726023
chr63656893436569070E068-49751
chr63656907236569457E068-49364
chr63657108336571181E068-47640
chr63657125136571655E068-47166
chr63657639136576518E068-42303
chr63657673236576818E068-42003
chr63657685036577747E068-41074
chr63659087836591641E068-27180
chr63659169636592086E068-26735
chr63659334736593599E068-25222
chr63660171336602187E068-16634
chr63660453336604803E068-14018
chr63660488636605053E068-13768
chr63661067636611542E068-7279
chr63663027636631038E06811455
chr63663108336631199E06812262
chr63663418336634271E06815362
chr63663445536634547E06815634
chr63663463736635354E06815816
chr63663550136635555E06816680
chr63664388736644663E06825066
chr63664484436645401E06826023
chr63664972036651350E06830899
chr63656893436569070E069-49751
chr63656907236569457E069-49364
chr63656958936569824E069-48997
chr63656988736570033E069-48788
chr63657685036577747E069-41074
chr63658464936585367E069-33454
chr63659087836591641E069-27180
chr63659334736593599E069-25222
chr63660171336602187E069-16634
chr63660453336604803E069-14018
chr63660488636605053E069-13768
chr63663418336634271E06915362
chr63663445536634547E06915634
chr63663463736635354E06915816
chr63664388736644663E06925066
chr63664484436645401E06926023
chr63656958936569824E070-48997
chr63656988736570033E070-48788
chr63657061936570669E070-48152
chr63657071036570840E070-47981
chr63657090836570968E070-47853
chr63657108336571181E070-47640
chr63657125136571655E070-47166
chr63657173436571941E070-46880
chr63657197436572080E070-46741
chr63657213936572192E070-46629
chr63657235136572436E070-46385
chr63657253836572695E070-46126
chr63657272436572801E070-46020
chr63657297636573042E070-45779
chr63657318136573365E070-45456
chr63657351736573763E070-45058
chr63657379436573915E070-44906
chr63657391736574003E070-44818
chr63656893436569070E071-49751
chr63656907236569457E071-49364
chr63657272436572801E071-46020
chr63657297636573042E071-45779
chr63657318136573365E071-45456
chr63657351736573763E071-45058
chr63657379436573915E071-44906
chr63657391736574003E071-44818
chr63657402736574106E071-44715
chr63657532136576117E071-42704
chr63657628836576390E071-42431
chr63657639136576518E071-42303
chr63658464936585367E071-33454
chr63658636236586585E071-32236
chr63658679436586933E071-31888
chr63659087836591641E071-27180
chr63659169636592086E071-26735
chr63659220936592331E071-26490
chr63659681236597095E071-21726
chr63659715736597418E071-21403
chr63660171336602187E071-16634
chr63660262636602741E071-16080
chr63660453336604803E071-14018
chr63660488636605053E071-13768
chr63661067636611542E071-7279
chr63661191936612010E071-6811
chr63662907136629121E07110250
chr63662913736629254E07110316
chr63663418336634271E07115362
chr63663445536634547E07115634
chr63663550136635555E07116680
chr63663566836635720E07116847
chr63663580136635845E07116980
chr63663651436636610E07117693
chr63663687136637086E07118050
chr63664484436645401E07126023
chr63656893436569070E072-49751
chr63656907236569457E072-49364
chr63656958936569824E072-48997
chr63656988736570033E072-48788
chr63657532136576117E072-42704
chr63658464936585367E072-33454
chr63659087836591641E072-27180
chr63660171336602187E072-16634
chr63660453336604803E072-14018
chr63660488636605053E072-13768
chr63661067636611542E072-7279
chr63663418336634271E07215362
chr63663445536634547E07215634
chr63663463736635354E07215816
chr63664484436645401E07226023
chr63657125136571655E073-47166
chr63658464936585367E073-33454
chr63659087836591641E073-27180
chr63659169636592086E073-26735
chr63659220936592331E073-26490
chr63659275536593308E073-25513
chr63659561636595993E073-22828
chr63660171336602187E073-16634
chr63661067636611542E073-7279
chr63662907136629121E07310250
chr63662913736629254E07310316
chr63663418336634271E07315362
chr63663445536634547E07315634
chr63663463736635354E07315816
chr63664484436645401E07326023
chr63656893436569070E074-49751
chr63656907236569457E074-49364
chr63656958936569824E074-48997
chr63656988736570033E074-48788
chr63657061936570669E074-48152
chr63657071036570840E074-47981
chr63657090836570968E074-47853
chr63657108336571181E074-47640
chr63657125136571655E074-47166
chr63657173436571941E074-46880
chr63657402736574106E074-44715
chr63657532136576117E074-42704
chr63657628836576390E074-42431
chr63657639136576518E074-42303
chr63657673236576818E074-42003
chr63657685036577747E074-41074
chr63658447036584530E074-34291
chr63658464936585367E074-33454
chr63659087836591641E074-27180
chr63659334736593599E074-25222
chr63659533836595462E074-23359
chr63659681236597095E074-21726
chr63659715736597418E074-21403
chr63660171336602187E074-16634
chr63660453336604803E074-14018
chr63660488636605053E074-13768
chr63662913736629254E07410316
chr63663418336634271E07415362
chr63663445536634547E07415634
chr63663463736635354E07415816
chr63664388736644663E07425066
chr63664484436645401E07426023
chr63656893436569070E081-49751
chr63656907236569457E081-49364
chr63657379436573915E081-44906
chr63657391736574003E081-44818
chr63657402736574106E081-44715
chr63657414236574202E081-44619
chr63657445336574540E081-44281
chr63657462736574755E081-44066
chr63657477436574896E081-43925
chr63658464936585367E081-33454
chr63659087836591641E081-27180
chr63659169636592086E081-26735
chr63659898136599730E081-19091
chr63660488636605053E081-13768
chr63660578736605835E081-12986
chr63657061936570669E082-48152
chr63657071036570840E082-47981
chr63657090836570968E082-47853
chr63657108336571181E082-47640
chr63657125136571655E082-47166
chr63657173436571941E082-46880
chr63657197436572080E082-46741
chr63657213936572192E082-46629
chr63657235136572436E082-46385
chr63657253836572695E082-46126
chr63657272436572801E082-46020
chr63657297636573042E082-45779
chr63657318136573365E082-45456
chr63657351736573763E082-45058
chr63657379436573915E082-44906
chr63657391736574003E082-44818
chr63657402736574106E082-44715
chr63657414236574202E082-44619
chr63657532136576117E082-42704
chr63657685036577747E082-41074
chr63658464936585367E082-33454
chr63659220936592331E082-26490
chr63660578736605835E082-12986










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr63662843336628957E0679612
chr63664541536649035E06726594
chr63664541536649035E06826594
chr63664541536649035E06926594
chr63664541536649035E07126594
chr63664541536649035E07226594
chr63662843336628957E0739612
chr63664541536649035E07326594
chr63662843336628957E0749612
chr63664541536649035E07426594
chr63662843336628957E0829612