rs13237006

Homo sapiens
A>G
MDFIC : 3 Prime UTR Variant
Check p-value
SNV (Single Nucleotide Variation)
G=0193 (5781/29906,GnomAD)
G=0168 (4910/29118,TOPMED)
G=0227 (1136/5008,1000G)
G=0209 (805/3854,ALSPAC)
G=0221 (820/3708,TWINSUK)
chr7:115018432 (GRCh38.p7) (7q31.2)
AD
GWASdb2
1   publication(s)
See rs on genome
13 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 7NC_000007.14:g.115018432A>G
GRCh37.p13 chr 7NC_000007.13:g.114658486A>G
MDFIC RefSeqGeneNG_029463.1:g.101278A>G

Gene: MDFIC, MyoD family inhibitor domain containing(plus strand)

Molecule type Change Amino acid[Codon] SO Term
MDFIC transcript variant 1NM_199072.4:c.N/A3 Prime UTR Variant
MDFIC transcript variant 1NM_001166345.1:c.N/A3 Prime UTR Variant
MDFIC transcript variant 2NM_001166346.1:c.N/AGenic Downstream Transcript Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.885G=0.115
1000GenomesAmericanSub694A=0.860G=0.140
1000GenomesEast AsianSub1008A=0.673G=0.327
1000GenomesEuropeSub1006A=0.795G=0.205
1000GenomesGlobalStudy-wide5008A=0.773G=0.227
1000GenomesSouth AsianSub978A=0.640G=0.360
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.791G=0.209
The Genome Aggregation DatabaseAfricanSub8724A=0.881G=0.119
The Genome Aggregation DatabaseAmericanSub836A=0.860G=0.140
The Genome Aggregation DatabaseEast AsianSub1606A=0.658G=0.342
The Genome Aggregation DatabaseEuropeSub18438A=0.783G=0.216
The Genome Aggregation DatabaseGlobalStudy-wide29906A=0.806G=0.193
The Genome Aggregation DatabaseOtherSub302A=0.760G=0.240
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.831G=0.168
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.779G=0.221
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs132370060.000436alcohol dependence21314694

eQTL of rs13237006 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs13237006 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr7114648478114649195E068-9291
chr7114649219114650397E068-8089
chr7114648478114649195E070-9291
chr7114649219114650397E070-8089
chr7114697219114697389E07038733
chr7114697510114697610E07039024
chr7114698827114699162E07040341
chr7114699210114699261E07040724
chr7114699384114699727E07040898
chr7114700345114700400E07041859
chr7114699210114699261E08140724
chr7114699384114699727E08140898
chr7114700980114701101E08142494