rs13250857

Homo sapiens
G>A
LOC101929268 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
A=0038 (1165/29984,GnomAD)
A=0033 (977/29118,TOPMED)
A=0046 (230/5008,1000G)
A=0053 (206/3854,ALSPAC)
A=0048 (177/3708,TWINSUK)
chr8:48583594 (GRCh38.p7) (8q11.21)
AD
GWASdb2
1   publication(s)
See rs on genome
34 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 8NC_000008.11:g.48583594G>A
GRCh37.p13 chr 8NC_000008.10:g.49496154G>A

Gene: LOC101929268, uncharacterized LOC101929268(plus strand)

Molecule type Change Amino acid[Codon] SO Term
LOC101929268 transcriptNR_105002.1:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.999A=0.001
1000GenomesAmericanSub694G=0.970A=0.030
1000GenomesEast AsianSub1008G=0.984A=0.016
1000GenomesEuropeSub1006G=0.953A=0.047
1000GenomesGlobalStudy-wide5008G=0.954A=0.046
1000GenomesSouth AsianSub978G=0.850A=0.150
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.947A=0.053
The Genome Aggregation DatabaseAfricanSub8732G=0.992A=0.008
The Genome Aggregation DatabaseAmericanSub838G=0.970A=0.030
The Genome Aggregation DatabaseEast AsianSub1618G=0.981A=0.019
The Genome Aggregation DatabaseEuropeSub18494G=0.944A=0.055
The Genome Aggregation DatabaseGlobalStudy-wide29984G=0.961A=0.038
The Genome Aggregation DatabaseOtherSub302G=0.970A=0.030
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.966A=0.033
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.952A=0.048
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs132508570.00098alcohol dependence20201924

eQTL of rs13250857 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs13250857 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr84946076949460833E068-35321
chr84946093949461019E068-35135
chr84946276249463854E070-32300
chr84953089349531201E07034739
chr84953133749531541E07035183
chr84953161549531669E07035461
chr84953170349531926E07035549
chr84953215749534246E07036003
chr84953426249534715E07038108
chr84944828549449134E081-47020
chr84944922049449590E081-46564
chr84946181549461874E081-34280
chr84946245149462537E081-33617
chr84946262449462712E081-33442
chr84946276249463854E081-32300
chr84946388249464068E081-32086
chr84946410849464300E081-31854
chr84946483749464881E081-31273
chr84946528249465376E081-30778
chr84946540949465459E081-30695
chr84946549049465541E081-30613
chr84946566149465776E081-30378
chr84946597249466049E081-30105
chr84946620949466378E081-29776
chr84946643549470720E081-25434
chr84949262649496781E0810
chr84953215749534246E08136003
chr84953426249534715E08138108
chr84946181549461874E082-34280
chr84946245149462537E082-33617
chr84946262449462712E082-33442
chr84946276249463854E082-32300
chr84946643549470720E082-25434
chr84953215749534246E08236003