rs13252510

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0093 (2748/29482,GnomAD)
A=0072 (2114/29118,TOPMED)
A=0095 (478/5008,1000G)
A=0117 (451/3854,ALSPAC)
A=0108 (402/3708,TWINSUK)
chr8:9908378 (GRCh38.p7) (8p23.1)
AD
GWASdb2
1   publication(s)
See rs on genome
43 Enhancers around
86 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 8NC_000008.11:g.9908378G>A
GRCh37.p13 chr 8NC_000008.10:g.9765888G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.992A=0.008
1000GenomesAmericanSub694G=0.860A=0.140
1000GenomesEast AsianSub1008G=0.834A=0.166
1000GenomesEuropeSub1006G=0.898A=0.102
1000GenomesGlobalStudy-wide5008G=0.905A=0.095
1000GenomesSouth AsianSub978G=0.890A=0.110
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.883A=0.117
The Genome Aggregation DatabaseAfricanSub8618G=0.973A=0.027
The Genome Aggregation DatabaseAmericanSub804G=0.880A=0.120
The Genome Aggregation DatabaseEast AsianSub1606G=0.824A=0.176
The Genome Aggregation DatabaseEuropeSub18154G=0.883A=0.116
The Genome Aggregation DatabaseGlobalStudy-wide29482G=0.906A=0.093
The Genome Aggregation DatabaseOtherSub300G=0.920A=0.080
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.927A=0.072
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.892A=0.108
PMID Title Author Journal
24277619ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.Quillen EEAm J Med Genet B Neuropsychiatr Genet

P-Value

SNP ID p-value Traits Study
rs132525100.000908alcohol consumption (maxi-drinks)24277619

eQTL of rs13252510 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs13252510 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr897423019742944E068-22944
chr897436329743683E068-22205
chr897575029758130E068-7758
chr897581969758595E068-7293
chr897662429766537E069354
chr897539299754031E070-11857
chr897540569754120E070-11768
chr897676129767703E0701724
chr897680079768268E0702119
chr897683979768479E0702509
chr897771929777312E07011304
chr897653079765384E073-504
chr897766139776832E07410725
chr897529469753045E081-12843
chr897532529753302E081-12586
chr897533179753442E081-12446
chr897537489753855E081-12033
chr897539299754031E081-11857
chr897540569754120E081-11768
chr897541759755248E081-10640
chr897573479757457E081-8431
chr897653079765384E081-504
chr897658469766219E0810
chr897662429766537E081354
chr897666379766694E081749
chr897667899766935E081901
chr897676129767703E0811724
chr897680079768268E0812119
chr897683979768479E0812509
chr897762319776296E08110343
chr897764259776476E08110537
chr897764919776587E08110603
chr897766139776832E08110725
chr897769299777002E08111041
chr897771929777312E08111304
chr897899249790017E08124036
chr898021769802287E08136288
chr898023389802435E08136450
chr898026369802928E08136748
chr898030839803201E08137195
chr898034379803487E08137549
chr898054049805475E08139516
chr897680079768268E0822119







Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr897587499759150E067-6738
chr897591809759298E067-6590
chr897594729759542E067-6346
chr897596249763076E067-2812
chr897630919765241E067-647
chr897749589775144E0679070
chr897752789775573E0679390
chr897757819775839E0679893
chr897758749775924E0679986
chr897911969791619E06725308
chr897587499759150E068-6738
chr897591809759298E068-6590
chr897594729759542E068-6346
chr897596249763076E068-2812
chr897630919765241E068-647
chr897738889773993E0688000
chr897744349774484E0688546
chr897749589775144E0689070
chr897752789775573E0689390
chr897757819775839E0689893
chr897758749775924E0689986
chr897911969791619E06825308
chr897917509791800E06825862
chr897587499759150E069-6738
chr897591809759298E069-6590
chr897594729759542E069-6346
chr897630919765241E069-647
chr897744349774484E0698546
chr897749589775144E0699070
chr897752789775573E0699390
chr897757819775839E0699893
chr897758749775924E0699986
chr897911969791619E06925308
chr897917509791800E06925862
chr897596249763076E070-2812
chr897630919765241E070-647
chr897757819775839E0709893
chr897758749775924E0709986
chr897911969791619E07025308
chr897917509791800E07025862
chr897587499759150E071-6738
chr897591809759298E071-6590
chr897594729759542E071-6346
chr897596249763076E071-2812
chr897630919765241E071-647
chr897757819775839E0719893
chr897758749775924E0719986
chr897911969791619E07125308
chr897917509791800E07125862
chr897587499759150E072-6738
chr897591809759298E072-6590
chr897594729759542E072-6346
chr897596249763076E072-2812
chr897630919765241E072-647
chr897752789775573E0729390
chr897757819775839E0729893
chr897758749775924E0729986
chr897911969791619E07225308
chr897917509791800E07225862
chr897587499759150E073-6738
chr897591809759298E073-6590
chr897594729759542E073-6346
chr897596249763076E073-2812
chr897630919765241E073-647
chr897738889773993E0738000
chr897744349774484E0738546
chr897749589775144E0739070
chr897752789775573E0739390
chr897757819775839E0739893
chr897758749775924E0739986
chr897911969791619E07325308
chr897917509791800E07325862
chr897596249763076E074-2812
chr897630919765241E074-647
chr897587499759150E081-6738
chr897591809759298E081-6590
chr897594729759542E081-6346
chr897596249763076E081-2812
chr897630919765241E081-647
chr897596249763076E082-2812
chr897630919765241E082-647
chr897752789775573E0829390
chr897757819775839E0829893
chr897758749775924E0829986
chr897911969791619E08225308
chr897917509791800E08225862