rs1338361

Homo sapiens
T>A / T>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0261 (7805/29798,GnomAD)
C=0195 (5678/29118,TOPMED)
C=0201 (1007/5008,1000G)
C=0339 (1305/3854,ALSPAC)
C=0326 (1208/3708,TWINSUK)
chr1:82730738 (GRCh38.p7) (1p31.1)
AD
GWASdb2
1   publication(s)
See rs on genome
32 Enhancers around
73 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 1NC_000001.11:g.82730738T>A
GRCh38.p7 chr 1NC_000001.11:g.82730738T>C
GRCh37.p13 chr 1NC_000001.10:g.83196421T>A
GRCh37.p13 chr 1NC_000001.10:g.83196421T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.967C=0.033
1000GenomesAmericanSub694T=0.750C=0.250
1000GenomesEast AsianSub1008T=0.766C=0.234
1000GenomesEuropeSub1006T=0.715C=0.285
1000GenomesGlobalStudy-wide5008T=0.799C=0.201
1000GenomesSouth AsianSub978T=0.730C=0.270
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.661C=0.339
The Genome Aggregation DatabaseAfricanSub8716T=0.924C=0.076
The Genome Aggregation DatabaseAmericanSub828T=0.740C=0.26,
The Genome Aggregation DatabaseEast AsianSub1522T=0.744C=0.256
The Genome Aggregation DatabaseEuropeSub18430T=0.648C=0.351
The Genome Aggregation DatabaseGlobalStudy-wide29798T=0.738C=0.261
The Genome Aggregation DatabaseOtherSub302T=0.780C=0.22,
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.805C=0.195
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.674C=0.326
PMID Title Author Journal
21703634A meta-analysis of two genome-wide association studies identifies 3 new loci for alcohol dependence.Wang KSJ Psychiatr Res

P-Value

SNP ID p-value Traits Study
rs13383615.74E-05alcohol dependence21703634

eQTL of rs1338361 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1338361 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr12183019921830440E06837549
chr12183050621830556E06837856
chr12183057621830634E06837926
chr12183078521830908E06838135
chr12176582921765879E069-26771
chr12183019921830440E06937549
chr12183050621830556E06937856
chr12183057621830634E06937926
chr12181792121818036E07025271
chr12181812721818231E07025477
chr12181825521818305E07025605
chr12181842921818733E07025779
chr12181877721818971E07026127
chr12183019921830440E07137549
chr12183050621830556E07137856
chr12183057621830634E07137926
chr12181726321817646E07224613
chr12181764721817738E07224997
chr12183019921830440E07237549
chr12183050621830556E07237856
chr12183057621830634E07237926
chr12183078521830908E07238135
chr12183019921830440E07337549
chr12183050621830556E07337856
chr12183057621830634E07337926
chr12183078521830908E07338135
chr12183820621838413E07345556
chr12183845721838829E07345807
chr12183019921830440E07437549
chr12183050621830556E07437856
chr12183057621830634E07437926
chr12176582921765879E081-26771








Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr12176302021763352E067-29298
chr12176343721764150E067-28500
chr12176618221766898E067-25752
chr12176694221767066E067-25584
chr12176714121767221E067-25429
chr12176729721767701E067-24949
chr12183517621836171E06742526
chr12183621621836508E06743566
chr12176302021763352E068-29298
chr12176343721764150E068-28500
chr12176618221766898E068-25752
chr12176694221767066E068-25584
chr12176714121767221E068-25429
chr12176729721767701E068-24949
chr12183517621836171E06842526
chr12183621621836508E06843566
chr12176285121762920E069-29730
chr12176302021763352E069-29298
chr12176343721764150E069-28500
chr12176618221766898E069-25752
chr12176694221767066E069-25584
chr12176714121767221E069-25429
chr12176729721767701E069-24949
chr12183517621836171E06942526
chr12183621621836508E06943566
chr12176302021763352E070-29298
chr12176343721764150E070-28500
chr12176618221766898E070-25752
chr12176694221767066E070-25584
chr12176714121767221E070-25429
chr12176729721767701E070-24949
chr12183517621836171E07042526
chr12183621621836508E07043566
chr12183656921836991E07043919
chr12176302021763352E071-29298
chr12176618221766898E071-25752
chr12176694221767066E071-25584
chr12176714121767221E071-25429
chr12176729721767701E071-24949
chr12183621621836508E07143566
chr12175477921755001E072-37649
chr12176302021763352E072-29298
chr12176343721764150E072-28500
chr12176618221766898E072-25752
chr12176694221767066E072-25584
chr12176714121767221E072-25429
chr12176729721767701E072-24949
chr12176302021763352E073-29298
chr12176343721764150E073-28500
chr12176618221766898E073-25752
chr12176694221767066E073-25584
chr12176714121767221E073-25429
chr12176729721767701E073-24949
chr12183517621836171E07342526
chr12183621621836508E07343566
chr12183656921836991E07343919
chr12176302021763352E074-29298
chr12176618221766898E074-25752
chr12176694221767066E074-25584
chr12176714121767221E074-25429
chr12176729721767701E074-24949
chr12176618221766898E081-25752
chr12176694221767066E081-25584
chr12176714121767221E081-25429
chr12176729721767701E081-24949
chr12176302021763352E082-29298
chr12176343721764150E082-28500
chr12176618221766898E082-25752
chr12176694221767066E082-25584
chr12176714121767221E082-25429
chr12176729721767701E082-24949
chr12183517621836171E08242526
chr12183621621836508E08243566