rs1340000

Homo sapiens
G>A / G>T
GPR158-AS1 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
A=0050 (1526/29970,GnomAD)
A=0080 (2337/29118,TOPMED)
A=0060 (298/5008,1000G)
A=0005 (19/3854,ALSPAC)
A=0006 (21/3708,TWINSUK)
chr10:25171834 (GRCh38.p7) (10p12.1)
AD
GWASdb2
1   publication(s)
See rs on genome
65 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 10NC_000010.11:g.25171834G>A
GRCh38.p7 chr 10NC_000010.11:g.25171834G>T
GRCh37.p13 chr 10NC_000010.10:g.25460763G>A
GRCh37.p13 chr 10NC_000010.10:g.25460763G>T

Gene: GPR158-AS1, GPR158 antisense RNA 1(minus strand)

Molecule type Change Amino acid[Codon] SO Term
GPR158-AS1 transcriptNR_027333.1:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.828A=0.172
1000GenomesAmericanSub694G=0.960A=0.040
1000GenomesEast AsianSub1008G=1.000A=0.000
1000GenomesEuropeSub1006G=0.995A=0.005
1000GenomesGlobalStudy-wide5008G=0.940A=0.060
1000GenomesSouth AsianSub978G=0.960A=0.040
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.995A=0.005
The Genome Aggregation DatabaseAfricanSub8722G=0.836A=0.164
The Genome Aggregation DatabaseAmericanSub838G=0.970A=0.030
The Genome Aggregation DatabaseEast AsianSub1622G=1.000A=0.000
The Genome Aggregation DatabaseEuropeSub18486G=0.996A=0.003
The Genome Aggregation DatabaseGlobalStudy-wide29970G=0.949A=0.050
The Genome Aggregation DatabaseOtherSub302G=0.990A=0.010
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.919A=0.080
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.994A=0.006
PMID Title Author Journal

P-Value

SNP ID p-value Traits Study
rs13400001.73E-20alcohol consumptionpha001400

eQTL of rs1340000 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1340000 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr10133558511133559394E0685239
chr10133572082133572185E06818810
chr10133574773133574828E06821501
chr10133574890133575312E06821618
chr10133558333133558443E0695061
chr10133558511133559394E0695239
chr10133559480133559593E0696208
chr10133575402133576550E06922130
chr10133508582133508684E070-44588
chr10133508696133508746E070-44526
chr10133508807133508948E070-44324
chr10133511950133511990E070-41282
chr10133512224133512274E070-40998
chr10133540367133540427E070-12845
chr10133540640133540787E070-12485
chr10133540886133541255E070-12017
chr10133541490133541603E070-11669
chr10133558101133558240E0704829
chr10133558333133558443E0705061
chr10133558511133559394E0705239
chr10133559480133559593E0706208
chr10133559687133559752E0706415
chr10133560034133560110E0706762
chr10133560266133560316E0706994
chr10133575402133576550E07022130
chr10133576610133576666E07023338
chr10133576677133577008E07023405
chr10133574890133575312E07121618
chr10133575402133576550E07122130
chr10133558101133558240E0724829
chr10133558333133558443E0725061
chr10133558511133559394E0725239
chr10133574705133574755E07221433
chr10133575402133576550E07222130
chr10133558333133558443E0735061
chr10133558511133559394E0735239
chr10133509007133509696E081-43576
chr10133522767133523162E081-30110
chr10133556196133556250E0812924
chr10133556398133556448E0813126
chr10133556533133556711E0813261
chr10133558333133558443E0815061
chr10133558511133559394E0815239
chr10133559480133559593E0816208
chr10133574773133574828E08121501
chr10133574890133575312E08121618
chr10133575402133576550E08122130
chr10133578541133578591E08125269
chr10133578725133578782E08125453
chr10133578849133579062E08125577
chr10133581100133581994E08127828
chr10133582184133582341E08128912
chr10133583571133583888E08130299
chr10133583958133584189E08130686
chr10133601277133601357E08148005
chr10133602191133602253E08148919
chr10133602333133602383E08149061
chr10133602423133602645E08149151
chr10133558333133558443E0825061
chr10133558511133559394E0825239
chr10133562751133562816E0829479
chr10133563318133563385E08210046
chr10133575402133576550E08222130
chr10133601660133601809E08248388
chr10133602423133602645E08249151