rs13400652

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0418 (12469/29774,GnomAD)
T=0367 (10706/29116,TOPMED)
T=0364 (1823/5008,1000G)
C==0480 (1849/3854,ALSPAC)
C==0482 (1787/3708,TWINSUK)
chr2:122638301 (GRCh38.p7) (2q14.3)
ND
GWASdb2
1   publication(s)
See rs on genome
10 Enhancers around
5 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 2NC_000002.12:g.122638301C>T
GRCh37.p13 chr 2NC_000002.11:g.123395877C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.843T=0.157
1000GenomesAmericanSub694C=0.560T=0.440
1000GenomesEast AsianSub1008C=0.610T=0.390
1000GenomesEuropeSub1006C=0.483T=0.517
1000GenomesGlobalStudy-wide5008C=0.636T=0.364
1000GenomesSouth AsianSub978C=0.600T=0.400
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.480T=0.520
The Genome Aggregation DatabaseAfricanSub8686C=0.791T=0.209
The Genome Aggregation DatabaseAmericanSub834C=0.520T=0.480
The Genome Aggregation DatabaseEast AsianSub1610C=0.618T=0.382
The Genome Aggregation DatabaseEuropeSub18342C=0.480T=0.520
The Genome Aggregation DatabaseGlobalStudy-wide29774C=0.581T=0.418
The Genome Aggregation DatabaseOtherSub302C=0.650T=0.350
Trans-Omics for Precision MedicineGlobalStudy-wide29116C=0.632T=0.367
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.482T=0.518
PMID Title Author Journal
19268276Genome-wide association study of smoking initiation and current smoking.Vink JMAm J Hum Genet

P-Value

SNP ID p-value Traits Study
rs134006525.72E-05nicotine smoking19268276

eQTL of rs13400652 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs13400652 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr2123401234123401751E0705357
chr2123410167123410719E08114290
chr2123410789123411053E08114912
chr2123421030123421470E08125153
chr2123421543123421587E08125666
chr2123421670123421860E08125793
chr2123444487123444661E08148610
chr2123421030123421470E08225153
chr2123421543123421587E08225666
chr2123421670123421860E08225793



Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr2123418348123419437E06722471
chr2123418348123419437E07022471
chr2123418348123419437E07222471
chr2123418348123419437E07422471
chr2123418348123419437E08222471