SNP Detail Info-rs13406625

Organism: Homo sapiens

Alleles: T>C

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

C=0089 (2591/29116,TOPMED)
C=0087 (2082/23674,GnomAD)
C=0096 (482/5008,1000G)
C=0042 (160/3854,ALSPAC)
C=0043 (158/3708,TWINSUK)

Position: chr2:56494872 (GRCh38.p7) (2p16.1)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 0 Enhancer around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 2	NC_000002.12:g.56494872T>C
GRCh37.p13 chr 2	NC_000002.11:g.56722007T>C

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	T=0.831	C=0.169
1000Genomes	American	Sub	694	T=0.880	C=0.120
1000Genomes	East Asian	Sub	1008	T=0.924	C=0.076
1000Genomes	Europe	Sub	1006	T=0.953	C=0.047
1000Genomes	Global	Study-wide	5008	T=0.904	C=0.096
1000Genomes	South Asian	Sub	978	T=0.950	C=0.050
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	T=0.958	C=0.042
The Genome Aggregation Database	African	Sub	7028	T=0.840	C=0.160
The Genome Aggregation Database	American	Sub	686	T=0.830	C=0.170
The Genome Aggregation Database	East Asian	Sub	1394	T=0.902	C=0.098
The Genome Aggregation Database	Europe	Sub	14306	T=0.951	C=0.048
The Genome Aggregation Database	Global	Study-wide	23674	T=0.912	C=0.087
The Genome Aggregation Database	Other	Sub	260	T=0.950	C=0.050
Trans-Omics for Precision Medicine	Global	Study-wide	29116	T=0.911	C=0.089
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	T=0.957	C=0.043

PMID	Title	Author	Journal
24277619	ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.	Quillen EE	Am J Med Genet B Neuropsychiatr Genet

SNP ID	p-value	Traits	Study
rs13406625	0.00074	alcohol consumption (maxi-drinks)	24277619

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

rs13406625