SNP Detail Info-rs1341260

Variant Details Frequency Publications p-values eSNP meSNP

Genomic Coordinates

Sequence Name	Change(s)
GRCh38.p7 chr 1	NC_000001.11:g.81898976T>C
GRCh37.p13 chr 1	NC_000001.10:g.82364661T>C

Gene: ADGRL2, adhesion G protein-coupled receptor L2(plus strand)

Molecule type	Change	Amino acid[Codon]	SO Term
ADGRL2 transcript variant 2	NM_001297704.1:c.	N/A	Intron Variant
ADGRL2 transcript variant 3	NM_001297705.1:c.	N/A	Intron Variant
ADGRL2 transcript variant 4	NM_001297706.1:c.	N/A	Intron Variant
ADGRL2 transcript variant 1	NM_012302.3:c.	N/A	Intron Variant
ADGRL2 transcript variant X7	XM_005270666.4:c.	N/A	Intron Variant
ADGRL2 transcript variant X10	XM_005270668.2:c.	N/A	Intron Variant
ADGRL2 transcript variant X1	XM_006710485.3:c.	N/A	Intron Variant
ADGRL2 transcript variant X2	XM_006710488.2:c.	N/A	Intron Variant
ADGRL2 transcript variant X4	XM_006710489.3:c.	N/A	Intron Variant
ADGRL2 transcript variant X2	XM_017000782.1:c.	N/A	Intron Variant
ADGRL2 transcript variant X3	XM_017000783.1:c.	N/A	Intron Variant
ADGRL2 transcript variant X3	XM_017000784.1:c.	N/A	Intron Variant
ADGRL2 transcript variant X7	XM_017000785.1:c.	N/A	Intron Variant
ADGRL2 transcript variant X6	XM_017000786.1:c.	N/A	Intron Variant
ADGRL2 transcript variant X9	XM_017000787.1:c.	N/A	Intron Variant
ADGRL2 transcript variant X11	XM_017000788.1:c.	N/A	Intron Variant
ADGRL2 transcript variant X12	XM_017000789.1:c.	N/A	Intron Variant
ADGRL2 transcript variant X14	XM_017000790.1:c.	N/A	Intron Variant
ADGRL2 transcript variant X15	XM_017000791.1:c.	N/A	Intron Variant
ADGRL2 transcript variant X16	XM_017000792.1:c.	N/A	Intron Variant
ADGRL2 transcript variant X20	XM_017000793.1:c.	N/A	Intron Variant
ADGRL2 transcript variant X23	XM_017000794.1:c.	N/A	Intron Variant
ADGRL2 transcript variant X24	XM_017000795.1:c.	N/A	Intron Variant
ADGRL2 transcript variant X14	XM_017000796.1:c.	N/A	Intron Variant
ADGRL2 transcript variant X26	XM_017000797.1:c.	N/A	Intron Variant
ADGRL2 transcript variant X27	XM_017000798.1:c.	N/A	Intron Variant
ADGRL2 transcript variant X17	XR_001737067.1:n.	N/A	Intron Variant
ADGRL2 transcript variant X18	XR_001737068.1:n.	N/A	Intron Variant
ADGRL2 transcript variant X19	XR_001737069.1:n.	N/A	Intron Variant
ADGRL2 transcript variant X21	XR_001737070.1:n.	N/A	Intron Variant
ADGRL2 transcript variant X22	XR_001737071.1:n.	N/A	Intron Variant

Population Frequency

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	T=0.927	C=0.073
1000Genomes	American	Sub	694	T=0.860	C=0.140
1000Genomes	East Asian	Sub	1008	T=0.962	C=0.038
1000Genomes	Europe	Sub	1006	T=0.791	C=0.209
1000Genomes	Global	Study-wide	5008	T=0.875	C=0.125
1000Genomes	South Asian	Sub	978	T=0.810	C=0.190
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	T=0.777	C=0.223
The Genome Aggregation Database	African	Sub	8724	T=0.910	C=0.090
The Genome Aggregation Database	American	Sub	838	T=0.830	C=0.170
The Genome Aggregation Database	East Asian	Sub	1614	T=0.947	C=0.053
The Genome Aggregation Database	Europe	Sub	18492	T=0.811	C=0.188
The Genome Aggregation Database	Global	Study-wide	29970	T=0.846	C=0.153
The Genome Aggregation Database	Other	Sub	302	T=0.630	C=0.370
Trans-Omics for Precision Medicine	Global	Study-wide	29118	T=0.840	C=0.159
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	T=0.783	C=0.217

PMID	Title	Author	Journal
17158188	Novel genes identified in a high-density genome wide association study for nicotine dependence.	Bierut LJ	Hum Mol Genet

P-Value

SNP ID	p-value	Traits	Study
rs1341260	0.000661	nicotine dependence	17158188

eQTL of rs1341260 in Brain tissues (GTEx Analysis Release V7)

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

meQTL of rs1341260 in Fetal Brain

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr1	82385835	82386483	E068	21174
chr1	82315043	82315226	E070	-49435
chr1	82351087	82351284	E070	-13377
chr1	82385835	82386483	E072	21174
chr1	82366262	82366312	E073	1601
chr1	82315043	82315226	E081	-49435
chr1	82343523	82343609	E081	-21052
chr1	82343773	82343929	E081	-20732
chr1	82348682	82348819	E081	-15842
chr1	82348991	82349090	E081	-15571
chr1	82318670	82319028	E082	-45633
chr1	82319151	82319221	E082	-45440
chr1	82344245	82344490	E082	-20171
chr1	82348415	82348465	E082	-16196
chr1	82348682	82348819	E082	-15842
chr1	82348991	82349090	E082	-15571

rs1341260

Genomic Coordinates

Gene: ADGRL2, adhesion G protein-coupled receptor L2(plus strand)

Population Frequency

P-Value

eQTL of rs1341260 in Brain tissues (GTEx Analysis Release V7)

meQTL of rs1341260 in Fetal Brain

Genomic View

Chromatin Interaction

Enhancer Annotation (GRCh37.p13)

Promoter Annotation (GRCh37.p13)