rs13425618

Homo sapiens
A>G
VWC2L : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
G=0227 (6792/29894,GnomAD)
G=0219 (6383/29118,TOPMED)
G=0227 (1137/5008,1000G)
G=0240 (924/3854,ALSPAC)
G=0231 (858/3708,TWINSUK)
chr2:214485443 (GRCh38.p7) (2q34)
AD
GWASdb2
1   publication(s)
See rs on genome
40 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 2NC_000002.12:g.214485443A>G
GRCh37.p13 chr 2NC_000002.11:g.215350167A>G

Gene: VWC2L, von Willebrand factor C domain containing protein 2-like(plus strand)

Molecule type Change Amino acid[Codon] SO Term
VWC2L transcriptNM_001080500.2:c.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.818G=0.182
1000GenomesAmericanSub694A=0.670G=0.330
1000GenomesEast AsianSub1008A=0.756G=0.244
1000GenomesEuropeSub1006A=0.770G=0.230
1000GenomesGlobalStudy-wide5008A=0.773G=0.227
1000GenomesSouth AsianSub978A=0.800G=0.200
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.760G=0.240
The Genome Aggregation DatabaseAfricanSub8698A=0.813G=0.187
The Genome Aggregation DatabaseAmericanSub836A=0.690G=0.310
The Genome Aggregation DatabaseEast AsianSub1608A=0.738G=0.262
The Genome Aggregation DatabaseEuropeSub18452A=0.761G=0.238
The Genome Aggregation DatabaseGlobalStudy-wide29894A=0.772G=0.227
The Genome Aggregation DatabaseOtherSub300A=0.720G=0.280
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.780G=0.219
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.769G=0.231
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs134256180.00088alcohol dependence20201924

eQTL of rs13425618 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs13425618 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr2215345728215345883E067-4284
chr2215346010215346232E067-3935
chr2215346603215346744E067-3423
chr2215347475215347884E067-2283
chr2215349103215349270E067-897
chr2215379495215379597E06729328
chr2215379599215379667E06729432
chr2215330046215330806E068-19361
chr2215345728215345883E068-4284
chr2215346010215346232E068-3935
chr2215346603215346744E068-3423
chr2215347475215347884E068-2283
chr2215345728215345883E069-4284
chr2215346010215346232E069-3935
chr2215346603215346744E069-3423
chr2215379495215379597E06929328
chr2215379599215379667E06929432
chr2215379495215379597E07029328
chr2215379599215379667E07029432
chr2215380137215380241E07029970
chr2215345728215345883E071-4284
chr2215346010215346232E071-3935
chr2215346603215346744E071-3423
chr2215347475215347884E071-2283
chr2215349103215349270E071-897
chr2215379599215379667E07129432
chr2215345728215345883E072-4284
chr2215346010215346232E072-3935
chr2215346603215346744E072-3423
chr2215347475215347884E072-2283
chr2215349103215349270E072-897
chr2215379495215379597E07229328
chr2215379599215379667E07229432
chr2215380137215380241E07229970
chr2215346010215346232E073-3935
chr2215345728215345883E074-4284
chr2215346010215346232E074-3935
chr2215346603215346744E074-3423
chr2215379495215379597E08129328
chr2215379599215379667E08129432