rs1349568

Homo sapiens
A>C
LOC105370467 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
A==0302 (9052/29924,GnomAD)
A==0251 (7335/29118,TOPMED)
A==0272 (1361/5008,1000G)
A==0378 (1456/3854,ALSPAC)
A==0371 (1377/3708,TWINSUK)
chr14:40846740 (GRCh38.p7) (14q21.1)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 14NC_000014.9:g.40846740A>C
GRCh37.p13 chr 14NC_000014.8:g.41315945A>C

Gene: LOC105370467, uncharacterized LOC105370467(plus strand)

Molecule type Change Amino acid[Codon] SO Term
LOC105370467 transcriptXR_001750739.1:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.049C=0.951
1000GenomesAmericanSub694A=0.380C=0.620
1000GenomesEast AsianSub1008A=0.330C=0.670
1000GenomesEuropeSub1006A=0.365C=0.635
1000GenomesGlobalStudy-wide5008A=0.272C=0.728
1000GenomesSouth AsianSub978A=0.340C=0.660
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.378C=0.622
The Genome Aggregation DatabaseAfricanSub8712A=0.107C=0.893
The Genome Aggregation DatabaseAmericanSub838A=0.360C=0.640
The Genome Aggregation DatabaseEast AsianSub1618A=0.318C=0.682
The Genome Aggregation DatabaseEuropeSub18454A=0.392C=0.607
The Genome Aggregation DatabaseGlobalStudy-wide29924A=0.302C=0.697
The Genome Aggregation DatabaseOtherSub302A=0.230C=0.770
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.251C=0.748
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.371C=0.629
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs13495680.00025alcohol dependence20201924

eQTL of rs1349568 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1349568 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.