rs1351734

Homo sapiens
T>C
TEX41 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
T==0272 (8111/29772,GnomAD)
T==0261 (7612/29118,TOPMED)
T==0279 (1399/5008,1000G)
T==0254 (979/3854,ALSPAC)
T==0252 (934/3708,TWINSUK)
chr2:144729026 (GRCh38.p7) (2q22.3)
AD
GWASdb2
1   publication(s)
See rs on genome
25 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 2NC_000002.12:g.144729026T>C
GRCh37.p13 chr 2NC_000002.11:g.145486593T>C

Gene: TEX41, testis expressed 41 (non-protein coding)(plus strand)

Molecule type Change Amino acid[Codon] SO Term
TEX41 transcriptNR_033870.2:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.340C=0.660
1000GenomesAmericanSub694T=0.240C=0.760
1000GenomesEast AsianSub1008T=0.227C=0.773
1000GenomesEuropeSub1006T=0.277C=0.723
1000GenomesGlobalStudy-wide5008T=0.279C=0.721
1000GenomesSouth AsianSub978T=0.280C=0.720
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.254C=0.746
The Genome Aggregation DatabaseAfricanSub8702T=0.317C=0.683
The Genome Aggregation DatabaseAmericanSub834T=0.190C=0.810
The Genome Aggregation DatabaseEast AsianSub1540T=0.195C=0.805
The Genome Aggregation DatabaseEuropeSub18394T=0.261C=0.738
The Genome Aggregation DatabaseGlobalStudy-wide29772T=0.272C=0.727
The Genome Aggregation DatabaseOtherSub302T=0.270C=0.730
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.261C=0.738
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.252C=0.748
PMID Title Author Journal
24277619ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.Quillen EEAm J Med Genet B Neuropsychiatr Genet

P-Value

SNP ID p-value Traits Study
rs13517340.000942alcohol consumption (maxi-drinks)24277619

eQTL of rs1351734 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1351734 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr2145439933145440509E067-46084
chr2145440773145440906E067-45687
chr2145465725145465850E067-20743
chr2145528417145529210E06741824
chr2145465725145465850E068-20743
chr2145533155145533236E06846562
chr2145533386145534023E06846793
chr2145465725145465850E069-20743
chr2145466243145466529E069-20064
chr2145465725145465850E070-20743
chr2145528417145529210E07041824
chr2145465366145465700E071-20893
chr2145466243145466529E071-20064
chr2145528417145529210E07141824
chr2145465725145465850E072-20743
chr2145466243145466529E072-20064
chr2145465366145465700E074-20893
chr2145465725145465850E074-20743
chr2145466243145466529E074-20064
chr2145528417145529210E07441824
chr2145469196145469276E081-17317
chr2145469357145469673E081-16920
chr2145469778145470030E081-16563
chr2145465366145465700E082-20893
chr2145465725145465850E082-20743