SNP Detail Info-rs1357096

Organism: Homo sapiens

Alleles: G>A

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

A=0321 (9509/29582,GnomAD)
A=0397 (11586/29118,TOPMED)
A=0295 (1477/5008,1000G)
A=0270 (1039/3854,ALSPAC)
A=0263 (975/3708,TWINSUK)

Position: chr12:78565116 (GRCh38.p7) (12q21.2)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 27 Enhancers around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 12	NC_000012.12:g.78565116G>A
GRCh37.p13 chr 12	NC_000012.11:g.78958896G>A

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	G=0.421	A=0.579
1000Genomes	American	Sub	694	G=0.740	A=0.260
1000Genomes	East Asian	Sub	1008	G=0.984	A=0.016
1000Genomes	Europe	Sub	1006	G=0.747	A=0.253
1000Genomes	Global	Study-wide	5008	G=0.705	A=0.295
1000Genomes	South Asian	Sub	978	G=0.740	A=0.260
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	G=0.730	A=0.270
The Genome Aggregation Database	African	Sub	8660	G=0.460	A=0.540
The Genome Aggregation Database	American	Sub	822	G=0.730	A=0.270
The Genome Aggregation Database	East Asian	Sub	1536	G=0.992	A=0.008
The Genome Aggregation Database	Europe	Sub	18262	G=0.754	A=0.245
The Genome Aggregation Database	Global	Study-wide	29582	G=0.678	A=0.321
The Genome Aggregation Database	Other	Sub	302	G=0.660	A=0.340
Trans-Omics for Precision Medicine	Global	Study-wide	29118	G=0.602	A=0.397
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	G=0.737	A=0.263

PMID	Title	Author	Journal
20201924	Genome-wide association study of alcohol dependence implicates a region on chromosome 11.	Edenberg HJ	Alcohol Clin Exp Res

SNP ID	p-value	Traits	Study
rs1357096	0.000818	alcohol dependence	20201924

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr12	78923698	78923909	E070	-34987
chr12	78923973	78924552	E070	-34344
chr12	78924704	78924986	E070	-33910
chr12	78925113	78925163	E070	-33733
chr12	78925525	78925679	E070	-33217
chr12	78925822	78925872	E070	-33024
chr12	78925953	78926003	E070	-32893
chr12	78926111	78926258	E070	-32638
chr12	78953226	78953418	E070	-5478
chr12	78953447	78953537	E070	-5359
chr12	78953687	78955340	E070	-3556
chr12	78953226	78953418	E081	-5478
chr12	78953447	78953537	E081	-5359
chr12	78953687	78955340	E081	-3556
chr12	78956270	78956675	E081	-2221
chr12	78956915	78956975	E081	-1921
chr12	78957048	78957256	E081	-1640
chr12	78957337	78957408	E081	-1488
chr12	78960147	78960527	E081	1251
chr12	78960716	78960851	E081	1820
chr12	78923698	78923909	E082	-34987
chr12	78923973	78924552	E082	-34344
chr12	78953226	78953418	E082	-5478
chr12	78953447	78953537	E082	-5359
chr12	78953687	78955340	E082	-3556
chr12	78958268	78958446	E082	-450
chr12	78958461	78958550	E082	-346

rs1357096