rs1357741

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0151 (4540/29956,GnomAD)
A=0180 (5257/29118,TOPMED)
A=0222 (1110/5008,1000G)
A=0052 (200/3854,ALSPAC)
A=0059 (218/3708,TWINSUK)
chr7:56223477 (GRCh38.p7) (7p11.2)
AD
GWASdb2
1   publication(s)
See rs on genome
2 Enhancers around
18 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 7NC_000007.14:g.56223477G>A
GRCh37.p13 chr 7NC_000007.13:g.56291170G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.588A=0.412
1000GenomesAmericanSub694G=0.910A=0.090
1000GenomesEast AsianSub1008G=0.780A=0.220
1000GenomesEuropeSub1006G=0.938A=0.062
1000GenomesGlobalStudy-wide5008G=0.778A=0.222
1000GenomesSouth AsianSub978G=0.780A=0.220
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.948A=0.052
The Genome Aggregation DatabaseAfricanSub8696G=0.686A=0.314
The Genome Aggregation DatabaseAmericanSub838G=0.920A=0.080
The Genome Aggregation DatabaseEast AsianSub1620G=0.767A=0.233
The Genome Aggregation DatabaseEuropeSub18500G=0.927A=0.072
The Genome Aggregation DatabaseGlobalStudy-wide29956G=0.848A=0.151
The Genome Aggregation DatabaseOtherSub302G=0.930A=0.070
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.819A=0.180
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.941A=0.059
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs13577410.00034alcohol dependence20201924

eQTL of rs1357741 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1357741 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr75632394556323985E07232775
chr75632435156324411E07233181

Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr75624269756243465E067-47705
chr75624357456243705E067-47465
chr75624269756243465E068-47705
chr75624357456243705E068-47465
chr75624269756243465E069-47705
chr75624357456243705E069-47465
chr75624232256242585E071-48585
chr75624269756243465E071-47705
chr75624357456243705E071-47465
chr75624232256242585E072-48585
chr75624269756243465E072-47705
chr75624357456243705E072-47465
chr75624232256242585E073-48585
chr75624269756243465E073-47705
chr75624357456243705E073-47465
chr75624269756243465E074-47705
chr75624357456243705E074-47465
chr75624269756243465E082-47705