rs1362571

Homo sapiens
G>A / G>T
FTO : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
G==0423 (12657/29864,GnomAD)
G==0408 (11904/29118,TOPMED)
G==0337 (1689/5008,1000G)
T=0470 (1811/3854,ALSPAC)
T=0451 (1674/3708,TWINSUK)
chr16:53877858 (GRCh38.p7) (16q12.2)
AD
GWASdb2
1   publication(s)
See rs on genome
196 Enhancers around
20 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 16NC_000016.10:g.53877858G>A
GRCh38.p7 chr 16NC_000016.10:g.53877858G>T
GRCh37.p13 chr 16NC_000016.9:g.53911770G>A
GRCh37.p13 chr 16NC_000016.9:g.53911770G>T
FTO RefSeqGeneNG_012969.1:g.178896G>A
FTO RefSeqGeneNG_012969.1:g.178896G>T

Gene: FTO, fat mass and obesity associated(plus strand)

Molecule type Change Amino acid[Codon] SO Term
FTO transcriptNM_001080432.2:c.N/AIntron Variant
FTO transcript variant X1XM_011523313.2:c.N/AIntron Variant
FTO transcript variant X4XM_011523314.2:c.N/AIntron Variant
FTO transcript variant X5XM_011523315.2:c.N/AIntron Variant
FTO transcript variant X6XM_011523316.2:c.N/AIntron Variant
FTO transcript variant X2XM_017023654.1:c.N/AIntron Variant
FTO transcript variant X3XM_017023655.1:c.N/AIntron Variant
FTO transcript variant X7XM_017023656.1:c.N/AIntron Variant
FTO transcript variant X8XM_017023657.1:c.N/AIntron Variant
FTO transcript variant X9XM_017023658.1:c.N/AGenic Downstream Transcript Variant
FTO transcript variant X10XR_001751980.1:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.167T=0.833
1000GenomesAmericanSub694G=0.350T=0.650
1000GenomesEast AsianSub1008G=0.148T=0.852
1000GenomesEuropeSub1006G=0.553T=0.447
1000GenomesGlobalStudy-wide5008G=0.337T=0.663
1000GenomesSouth AsianSub978G=0.530T=0.470
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.530T=0.470
The Genome Aggregation DatabaseAfricanSub8698G=0.234T=0.766
The Genome Aggregation DatabaseAmericanSub838G=0.330T=0.670
The Genome Aggregation DatabaseEast AsianSub1610G=0.138T=0.862
The Genome Aggregation DatabaseEuropeSub18418G=0.537T=0.462
The Genome Aggregation DatabaseGlobalStudy-wide29864G=0.423T=0.576
The Genome Aggregation DatabaseOtherSub300G=0.720T=0.280
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.408T=0.591
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.549T=0.451
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs13625710.000762alcohol dependence21314694

eQTL of rs1362571 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1362571 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr161200406412004412E067-44415
chr161200452812004642E067-44185
chr161200473612004822E067-44005
chr161200483612004880E067-43947
chr161200510212005191E067-43636
chr161200664412006705E067-42122
chr161200676512006893E067-41934
chr161200693812007047E067-41780
chr161205852512058625E0679698
chr161205882612058911E0679999
chr161205894012059036E06710113
chr161205903812059287E06710211
chr161206928612069422E06720459
chr161207211412072454E06723287
chr161208009312080267E06731266
chr161208398312084203E06735156
chr161208457812085168E06735751
chr161208804212088919E06739215
chr161209463712094909E06745810
chr161200406412004412E068-44415
chr161200452812004642E068-44185
chr161200473612004822E068-44005
chr161200483612004880E068-43947
chr161200510212005191E068-43636
chr161200633212006427E068-42400
chr161200645712006519E068-42308
chr161200664412006705E068-42122
chr161200676512006893E068-41934
chr161200693812007047E068-41780
chr161205852512058625E0689698
chr161205882612058911E0689999
chr161205894012059036E06810113
chr161205903812059287E06810211
chr161207211412072454E06823287
chr161207255812072608E06823731
chr161208259112082672E06833764
chr161208272112082771E06833894
chr161208313512083260E06834308
chr161208398312084203E06835156
chr161208457812085168E06835751
chr161208804212088919E06839215
chr161209394812093998E06845121
chr161209402212094326E06845195
chr161200406412004412E069-44415
chr161200452812004642E069-44185
chr161200473612004822E069-44005
chr161200483612004880E069-43947
chr161200693812007047E069-41780
chr161205894012059036E06910113
chr161205903812059287E06910211
chr161207211412072454E06923287
chr161207255812072608E06923731
chr161208259112082672E06933764
chr161208272112082771E06933894
chr161208313512083260E06934308
chr161208398312084203E06935156
chr161208457812085168E06935751
chr161208757712087617E06938750
chr161208804212088919E06939215
chr161208915012089200E06940323
chr161208929312089387E06940466
chr161209394812093998E06945121
chr161209402212094326E06945195
chr161209463712094909E06945810
chr161200664412006705E070-42122
chr161207211412072454E07023287
chr161207388212073932E07025055
chr161209629012096906E07047463
chr161200406412004412E071-44415
chr161200452812004642E071-44185
chr161200473612004822E071-44005
chr161200483612004880E071-43947
chr161200633212006427E071-42400
chr161200645712006519E071-42308
chr161200664412006705E071-42122
chr161200676512006893E071-41934
chr161200693812007047E071-41780
chr161205852512058625E0719698
chr161205882612058911E0719999
chr161205894012059036E07110113
chr161205903812059287E07110211
chr161206928612069422E07120459
chr161207211412072454E07123287
chr161207255812072608E07123731
chr161208259112082672E07133764
chr161208272112082771E07133894
chr161208398312084203E07135156
chr161208457812085168E07135751
chr161208586112085919E07137034
chr161208619512086354E07137368
chr161208639912086442E07137572
chr161208712312087295E07138296
chr161208757712087617E07138750
chr161208804212088919E07139215
chr161208915012089200E07140323
chr161208929312089387E07140466
chr161208956412089614E07140737
chr161209256012092645E07143733
chr161209284912092937E07144022
chr161209307412093124E07144247
chr161209315012093200E07144323
chr161209394812093998E07145121
chr161209402212094326E07145195
chr161209463712094909E07145810
chr161209629012096906E07147463
chr161200294712003216E072-45611
chr161200322812003285E072-45542
chr161200338912003447E072-45380
chr161200366612003753E072-45074
chr161200406412004412E072-44415
chr161200452812004642E072-44185
chr161200473612004822E072-44005
chr161200483612004880E072-43947
chr161200664412006705E072-42122
chr161200676512006893E072-41934
chr161200693812007047E072-41780
chr161205824312058397E0729416
chr161205852512058625E0729698
chr161205882612058911E0729999
chr161205894012059036E07210113
chr161205903812059287E07210211
chr161207211412072454E07223287
chr161207255812072608E07223731
chr161208259112082672E07233764
chr161208272112082771E07233894
chr161208398312084203E07235156
chr161208457812085168E07235751
chr161208804212088919E07239215
chr161208915012089200E07240323
chr161208929312089387E07240466
chr161209024412090294E07241417
chr161209044512090505E07241618
chr161209394812093998E07245121
chr161209402212094326E07245195
chr161200104212001092E073-47735
chr161200109612001161E073-47666
chr161200141712001606E073-47221
chr161200163512001757E073-47070
chr161200406412004412E073-44415
chr161200452812004642E073-44185
chr161200473612004822E073-44005
chr161200483612004880E073-43947
chr161200510212005191E073-43636
chr161200522412005321E073-43506
chr161200676512006893E073-41934
chr161200693812007047E073-41780
chr161206928612069422E07320459
chr161207211412072454E07323287
chr161207255812072608E07323731
chr161208358212083687E07334755
chr161208398312084203E07335156
chr161208804212088919E07339215
chr161209394812093998E07345121
chr161200452812004642E074-44185
chr161200473612004822E074-44005
chr161200483612004880E074-43947
chr161200664412006705E074-42122
chr161200676512006893E074-41934
chr161200693812007047E074-41780
chr161205852512058625E0749698
chr161205882612058911E0749999
chr161205894012059036E07410113
chr161205903812059287E07410211
chr161207211412072454E07423287
chr161207255812072608E07423731
chr161208259112082672E07433764
chr161208272112082771E07433894
chr161208313512083260E07434308
chr161208398312084203E07435156
chr161208457812085168E07435751
chr161208586112085919E07437034
chr161208757712087617E07438750
chr161208804212088919E07439215
chr161208915012089200E07440323
chr161208929312089387E07440466
chr161209024412090294E07441417
chr161209044512090505E07441618
chr161209082612090969E07441999
chr161209098312091079E07442156
chr161209115712091237E07442330
chr161209394812093998E07445121
chr161200483612004880E081-43947
chr161200633212006427E081-42400
chr161200645712006519E081-42308
chr161200664412006705E081-42122
chr161200676512006893E081-41934
chr161200693812007047E081-41780
chr161206928612069422E08120459
chr161207211412072454E08123287
chr161208009312080267E08131266
chr161209629012096906E08147463
chr161200473612004822E082-44005
chr161200483612004880E082-43947
chr161200633212006427E082-42400
chr161200645712006519E082-42308
chr161200664412006705E082-42122










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr161200719512011040E067-37787
chr161207006112071981E06721234
chr161200719512011040E068-37787
chr161207006112071981E06821234
chr161200719512011040E069-37787
chr161207006112071981E06921234
chr161200719512011040E070-37787
chr161207006112071981E07021234
chr161200719512011040E071-37787
chr161207006112071981E07121234
chr161200719512011040E072-37787
chr161207006112071981E07221234
chr161200719512011040E073-37787
chr161207006112071981E07321234
chr161200719512011040E074-37787
chr161207006112071981E07421234
chr161200719512011040E081-37787
chr161207006112071981E08121234
chr161200719512011040E082-37787
chr161207006112071981E08221234