SNP Detail Info-rs1365507

Organism: Homo sapiens

Alleles: A>G

Gene : Feature

SLC27A2 : Intron Variant

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

G=0063 (1901/29966,GnomAD)
G=0089 (2594/29118,TOPMED)
G=0075 (375/5008,1000G)
G=0023 (87/3854,ALSPAC)
G=0021 (78/3708,TWINSUK)

Position: chr15:50185038 (GRCh38.p7) (15q21.2)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 4 Enhancers around

Promoter: 8 Promoters around

Sequence Name	Change(s)
GRCh38.p7 chr 15	NC_000015.10:g.50185038A>G
GRCh37.p13 chr 15	NC_000015.9:g.50477235A>G

Molecule type	Change	Amino acid[Codon]	SO Term
SLC27A2 transcript variant 2	NM_001159629.1:c.	N/A	Intron Variant
SLC27A2 transcript variant 1	NM_003645.3:c.	N/A	Intron Variant

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	A=0.819	G=0.181
1000Genomes	American	Sub	694	A=0.960	G=0.040
1000Genomes	East Asian	Sub	1008	A=0.995	G=0.005
1000Genomes	Europe	Sub	1006	A=0.974	G=0.026
1000Genomes	Global	Study-wide	5008	A=0.925	G=0.075
1000Genomes	South Asian	Sub	978	A=0.920	G=0.080
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	A=0.977	G=0.023
The Genome Aggregation Database	African	Sub	8712	A=0.828	G=0.172
The Genome Aggregation Database	American	Sub	838	A=0.970	G=0.030
The Genome Aggregation Database	East Asian	Sub	1620	A=0.993	G=0.007
The Genome Aggregation Database	Europe	Sub	18494	A=0.980	G=0.019
The Genome Aggregation Database	Global	Study-wide	29966	A=0.936	G=0.063
The Genome Aggregation Database	Other	Sub	302	A=0.970	G=0.030
Trans-Omics for Precision Medicine	Global	Study-wide	29118	A=0.910	G=0.089
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	A=0.979	G=0.021

PMID	Title	Author	Journal
21314694	Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.	Kendler KS	Alcohol Clin Exp Res

SNP ID	p-value	Traits	Study
rs1365507	0.000689	alcohol dependence	21314694

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr15	50475536	50475748	E067	-1487
chr15	50475749	50475936	E067	-1299
chr15	50437462	50438018	E071	-39217
chr15	50475536	50475748	E082	-1487

Chromosome	Start	End	Region	Distance(-/+:Up/Downstream)
chr15	50473623	50475391	E067	-1844
chr15	50473623	50475391	E068	-1844
chr15	50473623	50475391	E069	-1844
chr15	50473623	50475391	E070	-1844
chr15	50473623	50475391	E072	-1844
chr15	50473623	50475391	E073	-1844
chr15	50473623	50475391	E074	-1844
chr15	50473623	50475391	E082	-1844

rs1365507