rs1365773

Homo sapiens
C>A
None
Check p-value
SNV (Single Nucleotide Variation)
C==0246 (7380/29952,GnomAD)
C==0262 (7630/29118,TOPMED)
C==0203 (1016/5008,1000G)
C==0249 (961/3854,ALSPAC)
C==0248 (919/3708,TWINSUK)
chr2:230144838 (GRCh38.p7) (2q37.1)
AD
GWASdb2
1   publication(s)
See rs on genome
23 Enhancers around
1 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 2NC_000002.12:g.230144838C>A
GRCh37.p13 chr 2NC_000002.11:g.231009554C>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.302A=0.698
1000GenomesAmericanSub694C=0.260A=0.740
1000GenomesEast AsianSub1008C=0.077A=0.923
1000GenomesEuropeSub1006C=0.258A=0.742
1000GenomesGlobalStudy-wide5008C=0.203A=0.797
1000GenomesSouth AsianSub978C=0.100A=0.900
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.249A=0.751
The Genome Aggregation DatabaseAfricanSub8708C=0.282A=0.718
The Genome Aggregation DatabaseAmericanSub838C=0.220A=0.780
The Genome Aggregation DatabaseEast AsianSub1620C=0.079A=0.921
The Genome Aggregation DatabaseEuropeSub18484C=0.246A=0.753
The Genome Aggregation DatabaseGlobalStudy-wide29952C=0.246A=0.753
The Genome Aggregation DatabaseOtherSub302C=0.170A=0.830
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.262A=0.738
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.248A=0.752
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs13657730.000757alcohol dependence20201924

eQTL of rs1365773 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1365773 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr2230993697230993982E067-15572
chr2231024644231025170E06715090
chr2231035333231035600E06725779
chr2231049762231050171E06740208
chr2231024644231025170E06815090
chr2231035160231035243E06825606
chr2231035333231035600E06825779
chr2230993697230993982E069-15572
chr2231024644231025170E06915090
chr2231035160231035243E06925606
chr2230994101230994492E071-15062
chr2231035333231035600E07125779
chr2231024644231025170E07215090
chr2231049762231050171E07240208
chr2230994101230994492E073-15062
chr2230996054230996366E073-13188
chr2231035333231035600E07325779
chr2230974738230974898E074-34656
chr2230993697230993982E074-15572
chr2230994101230994492E074-15062
chr2231024644231025170E07415090
chr2231049762231050171E07440208
chr2230988840230989223E081-20331








Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr2230993530230993690E068-15864