rs1368882

Homo sapiens
G>A
MROH7 : 2KB Upstream Variant
MROH7-TTC4 : 2KB Upstream Variant
Check p-value
SNV (Single Nucleotide Variation)
A=0355 (10631/29912,GnomAD)
A=0320 (9321/29118,TOPMED)
A=0398 (1991/5008,1000G)
A=0398 (1533/3854,ALSPAC)
A=0373 (1384/3708,TWINSUK)
chr1:54641346 (GRCh38.p7) (1p32.3)
AD | ND
GWASdb2
1   publication(s)
See rs on genome
26 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 1NC_000001.11:g.54641346G>A
GRCh37.p13 chr 1NC_000001.10:g.55107019G>A

Gene: MROH7, maestro heat like repeat family member 7(plus strand): 2KB Upstream Variant

Molecule type Change Amino acid[Codon] SO Term
MROH7 transcript variant 1NM_001039464.3:c.N/AUpstream Transcript Variant
MROH7 transcript variant 3NM_001291332.1:c.N/AUpstream Transcript Variant
MROH7 transcript variant 2NR_026782.2:n.N/AUpstream Transcript Variant
MROH7 transcript variant 4NR_111931.1:n.N/AUpstream Transcript Variant

Gene: MROH7-TTC4, MROH7-TTC4 readthrough (NMD candidate)(plus strand): 2KB Upstream Variant

Molecule type Change Amino acid[Codon] SO Term
MROH7-TTC4 transcript variant 1NR_037639.2:n.N/AUpstream Transcript Variant
MROH7-TTC4 transcript variant 2NR_037640.2:n.N/AUpstream Transcript Variant
MROH7-TTC4 transcript variant 3NR_037641.2:n.N/AUpstream Transcript Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.771A=0.229
1000GenomesAmericanSub694G=0.540A=0.460
1000GenomesEast AsianSub1008G=0.517A=0.483
1000GenomesEuropeSub1006G=0.645A=0.355
1000GenomesGlobalStudy-wide5008G=0.602A=0.398
1000GenomesSouth AsianSub978G=0.470A=0.530
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.602A=0.398
The Genome Aggregation DatabaseAfricanSub8706G=0.750A=0.250
The Genome Aggregation DatabaseAmericanSub836G=0.520A=0.480
The Genome Aggregation DatabaseEast AsianSub1614G=0.495A=0.505
The Genome Aggregation DatabaseEuropeSub18454G=0.612A=0.387
The Genome Aggregation DatabaseGlobalStudy-wide29912G=0.644A=0.355
The Genome Aggregation DatabaseOtherSub302G=0.710A=0.290
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.679A=0.320
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.627A=0.373
PMID Title Author Journal
23942779A genome-wide association study of behavioral disinhibition.McGue MBehav Genet

P-Value

SNP ID p-value Traits Study
rs13688820.00021nicotine use23942779
rs13688820.00029alcohol dependence23942779

eQTL of rs1368882 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1368882 in Fetal Brain

Probe ID Position Gene beta p-value
cg01517571chr1:55089959ACOT11|FAM151A0.0497876363255322.3290e-11

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr15507508655075606E067-31413
chr15509301155093103E068-13916
chr15509723255097272E068-9747
chr15514681855146935E06839799
chr15514702455147118E06840005
chr15514714355147342E06840124
chr15514756555147605E06840546
chr15507508655075606E069-31413
chr15514702455147118E07040005
chr15514714355147342E07040124
chr15514756555147605E07040546
chr15507508655075606E071-31413
chr15509723255097272E071-9747
chr15507508655075606E072-31413
chr15507577055076117E072-30902
chr15507508655075606E073-31413
chr15507508655075606E074-31413
chr15507577055076117E074-30902
chr15506673255067414E081-39605
chr15514681855146935E08139799
chr15514702455147118E08140005
chr15514714355147342E08140124
chr15514681855146935E08239799
chr15514702455147118E08240005
chr15514714355147342E08240124
chr15514756555147605E08240546