rs1377943

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
C==0251 (7519/29932,GnomAD)
C==0280 (8176/29118,TOPMED)
C==0286 (1432/5008,1000G)
C==0159 (611/3854,ALSPAC)
C==0174 (644/3708,TWINSUK)
chr4:183008428 (GRCh38.p7) (4q35.1)
AD
GWASdb2
1   publication(s)
See rs on genome
1 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 4NC_000004.12:g.183008428C>T
GRCh37.p13 chr 4NC_000004.11:g.183929581C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.467T=0.533
1000GenomesAmericanSub694C=0.150T=0.850
1000GenomesEast AsianSub1008C=0.285T=0.715
1000GenomesEuropeSub1006C=0.206T=0.794
1000GenomesGlobalStudy-wide5008C=0.286T=0.714
1000GenomesSouth AsianSub978C=0.220T=0.780
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.159T=0.841
The Genome Aggregation DatabaseAfricanSub8698C=0.394T=0.606
The Genome Aggregation DatabaseAmericanSub838C=0.150T=0.850
The Genome Aggregation DatabaseEast AsianSub1618C=0.280T=0.720
The Genome Aggregation DatabaseEuropeSub18476C=0.188T=0.812
The Genome Aggregation DatabaseGlobalStudy-wide29932C=0.251T=0.748
The Genome Aggregation DatabaseOtherSub302C=0.150T=0.850
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.280T=0.719
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.174T=0.826
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs13779430.000962alcohol dependence21314694

eQTL of rs1377943 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1377943 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr4183932469183932936E0682888