rs1412428

Homo sapiens
G>A
LOC105376214 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
A=0263 (7900/29946,GnomAD)
A=0234 (6837/29118,TOPMED)
A=0222 (1114/5008,1000G)
A=0283 (1092/3854,ALSPAC)
A=0302 (1121/3708,TWINSUK)
chr9:108178039 (GRCh38.p7) (9q31.2)
AD
GWASdb2
1   publication(s)
See rs on genome
52 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 9NC_000009.12:g.108178039G>A
GRCh37.p13 chr 9NC_000009.11:g.110940319G>A

Gene: LOC105376214, uncharacterized LOC105376214(minus strand)

Molecule type Change Amino acid[Codon] SO Term
LOC105376214 transcript variant X1XR_001746881.1:n.N/AIntron Variant
LOC105376214 transcript variant X2XR_001746882.1:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.852A=0.148
1000GenomesAmericanSub694G=0.710A=0.290
1000GenomesEast AsianSub1008G=0.927A=0.073
1000GenomesEuropeSub1006G=0.692A=0.308
1000GenomesGlobalStudy-wide5008G=0.778A=0.222
1000GenomesSouth AsianSub978G=0.660A=0.340
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.717A=0.283
The Genome Aggregation DatabaseAfricanSub8720G=0.825A=0.175
The Genome Aggregation DatabaseAmericanSub838G=0.720A=0.280
The Genome Aggregation DatabaseEast AsianSub1614G=0.946A=0.054
The Genome Aggregation DatabaseEuropeSub18472G=0.675A=0.324
The Genome Aggregation DatabaseGlobalStudy-wide29946G=0.736A=0.263
The Genome Aggregation DatabaseOtherSub302G=0.800A=0.200
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.765A=0.234
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.698A=0.302
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs14124280.000364alcohol dependence20201924

eQTL of rs1412428 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1412428 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr9110904423110905551E067-34768
chr9110915781110915929E067-24390
chr9110949050110950053E0678731
chr9110969666110970473E06729347
chr9110904285110904390E068-35929
chr9110904423110905551E068-34768
chr9110905742110905796E068-34523
chr9110912998110913916E068-26403
chr9110969666110970473E06829347
chr9110904285110904390E069-35929
chr9110904423110905551E069-34768
chr9110948825110949001E0698506
chr9110949050110950053E0698731
chr9110950771110952024E06910452
chr9110904423110905551E070-34768
chr9110948699110948749E0708380
chr9110948825110949001E0708506
chr9110949050110950053E0708731
chr9110969666110970473E07029347
chr9110987094110987597E07046775
chr9110987678110987790E07047359
chr9110904423110905551E071-34768
chr9110912998110913916E071-26403
chr9110915781110915929E071-24390
chr9110916136110916412E071-23907
chr9110948825110949001E0718506
chr9110949050110950053E0718731
chr9110950771110952024E07110452
chr9110904423110905551E072-34768
chr9110905742110905796E072-34523
chr9110949050110950053E0728731
chr9110969666110970473E07229347
chr9110904423110905551E073-34768
chr9110969666110970473E07329347
chr9110903482110903536E074-36783
chr9110904103110904168E074-36151
chr9110904285110904390E074-35929
chr9110904423110905551E074-34768
chr9110905742110905796E074-34523
chr9110949050110950053E0748731
chr9110969666110970473E07429347
chr9110904423110905551E081-34768
chr9110920534110920737E081-19582
chr9110920741110921156E081-19163
chr9110921351110921479E081-18840
chr9110899342110899805E082-40514
chr9110899878110899954E082-40365
chr9110900333110900387E082-39932
chr9110900400110900459E082-39860
chr9110904423110905551E082-34768
chr9110911821110911938E082-28381
chr9110987094110987597E08246775