SNP Detail Info-rs1425465

Organism: Homo sapiens

Alleles: A>G

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

G=0471 (14087/29852,GnomAD)
G=0480 (14000/29118,TOPMED)
G=0466 (2335/5008,1000G)
G=0496 (1913/3854,ALSPAC)
A==0493 (1829/3708,TWINSUK)

Position: chr4:35558018 (GRCh38.p7) (4p15.1)

Phenotype: ND

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 3 Enhancers around

Promoter: 14 Promoters around

Sequence Name	Change(s)
GRCh38.p7 chr 4	NC_000004.12:g.35558018A>G
GRCh37.p13 chr 4	NC_000004.11:g.35559640A>G

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	A=0.554	G=0.446
1000Genomes	American	Sub	694	A=0.480	G=0.520
1000Genomes	East Asian	Sub	1008	A=0.704	G=0.296
1000Genomes	Europe	Sub	1006	A=0.526	G=0.474
1000Genomes	Global	Study-wide	5008	A=0.534	G=0.466
1000Genomes	South Asian	Sub	978	A=0.380	G=0.620
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	A=0.504	G=0.496
The Genome Aggregation Database	African	Sub	8698	A=0.550	G=0.450
The Genome Aggregation Database	American	Sub	836	A=0.430	G=0.570
The Genome Aggregation Database	East Asian	Sub	1616	A=0.743	G=0.257
The Genome Aggregation Database	Europe	Sub	18402	A=0.502	G=0.497
The Genome Aggregation Database	Global	Study-wide	29852	A=0.528	G=0.471
The Genome Aggregation Database	Other	Sub	300	A=0.570	G=0.430
Trans-Omics for Precision Medicine	Global	Study-wide	29118	A=0.519	G=0.480
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	A=0.493	G=0.507

PMID	Title	Author	Journal
17158188	Novel genes identified in a high-density genome wide association study for nicotine dependence.	Bierut LJ	Hum Mol Genet

SNP ID	p-value	Traits	Study
rs1425465	0.000191	nicotine dependence	17158188

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr4	35526737	35526787	E074	-32853
chr4	35536701	35536912	E082	-22728
chr4	35536998	35537160	E082	-22480

Chromosome	Start	End	Region	Distance(-/+:Up/Downstream)
chr4	35526872	35526986	E068	-32654
chr4	35527034	35527236	E068	-32404
chr4	35527533	35527608	E068	-32032
chr4	35526872	35526986	E069	-32654
chr4	35527034	35527236	E069	-32404
chr4	35526872	35526986	E071	-32654
chr4	35527034	35527236	E071	-32404
chr4	35527533	35527608	E071	-32032
chr4	35526872	35526986	E072	-32654
chr4	35527034	35527236	E072	-32404
chr4	35526872	35526986	E073	-32654
chr4	35527034	35527236	E073	-32404
chr4	35526872	35526986	E074	-32654
chr4	35527034	35527236	E074	-32404

rs1425465