rs1431031

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0230 (6907/29914,GnomAD)
C=0220 (6413/29118,TOPMED)
C=0212 (1061/5008,1000G)
C=0282 (1088/3854,ALSPAC)
C=0282 (1045/3708,TWINSUK)
chr14:41315498 (GRCh38.p7) (14q21.1)
ND
GWASdb2
1   publication(s)
See rs on genome
3 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 14NC_000014.9:g.41315498T>C
GRCh37.p13 chr 14NC_000014.8:g.41784701T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.875C=0.125
1000GenomesAmericanSub694T=0.790C=0.210
1000GenomesEast AsianSub1008T=0.834C=0.166
1000GenomesEuropeSub1006T=0.743C=0.257
1000GenomesGlobalStudy-wide5008T=0.788C=0.212
1000GenomesSouth AsianSub978T=0.670C=0.330
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.718C=0.282
The Genome Aggregation DatabaseAfricanSub8718T=0.818C=0.182
The Genome Aggregation DatabaseAmericanSub832T=0.830C=0.170
The Genome Aggregation DatabaseEast AsianSub1602T=0.808C=0.192
The Genome Aggregation DatabaseEuropeSub18460T=0.740C=0.259
The Genome Aggregation DatabaseGlobalStudy-wide29914T=0.769C=0.230
The Genome Aggregation DatabaseOtherSub302T=0.750C=0.250
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.779C=0.220
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.718C=0.282
PMID Title Author Journal
17158188Novel genes identified in a high-density genome wide association study for nicotine dependence.Bierut LJHum Mol Genet

P-Value

SNP ID p-value Traits Study
rs14310310.000297nicotine dependence17158188

eQTL of rs1431031 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1431031 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr144175450541754720E070-29981
chr144174720041747372E081-37329
chr144174720041747372E082-37329