SNP Detail Info-rs1433761

Organism: Homo sapiens

Alleles: A>C

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

C=0487 (14510/29776,GnomAD)
C=0487 (14194/29118,TOPMED)
C=0470 (2356/5008,1000G)
A==0492 (1896/3854,ALSPAC)
C=0491 (1822/3708,TWINSUK)

Position: chr1:82666717 (GRCh38.p7) (1p31.1)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 0 Enhancer around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 1	NC_000001.11:g.82666717A>C
GRCh37.p13 chr 1	NC_000001.10:g.83132400A>C

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	A=0.483	C=0.517
1000Genomes	American	Sub	694	A=0.450	C=0.550
1000Genomes	East Asian	Sub	1008	A=0.644	C=0.356
1000Genomes	Europe	Sub	1006	A=0.555	C=0.445
1000Genomes	Global	Study-wide	5008	A=0.530	C=0.470
1000Genomes	South Asian	Sub	978	A=0.510	C=0.490
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	A=0.492	C=0.508
The Genome Aggregation Database	African	Sub	8652	A=0.484	C=0.516
The Genome Aggregation Database	American	Sub	834	A=0.520	C=0.480
The Genome Aggregation Database	East Asian	Sub	1600	A=0.642	C=0.357
The Genome Aggregation Database	Europe	Sub	18388	A=0.513	C=0.486
The Genome Aggregation Database	Global	Study-wide	29776	A=0.512	C=0.487
The Genome Aggregation Database	Other	Sub	302	A=0.580	C=0.420
Trans-Omics for Precision Medicine	Global	Study-wide	29118	A=0.512	C=0.487
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	A=0.509	C=0.491

PMID	Title	Author	Journal
21703634	A meta-analysis of two genome-wide association studies identifies 3 new loci for alcohol dependence.	Wang KS	J Psychiatr Res

SNP ID	p-value	Traits	Study
rs1433761	9.33E-05	alcohol dependence	21703634

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

rs1433761