SNP Detail Info-rs1436899

Variant Details Frequency Publications p-values eSNP meSNP

Genomic Coordinates

Sequence Name	Change(s)
GRCh38.p7 chr 1	NC_000001.11:g.216884140A>G
GRCh37.p13 chr 1	NC_000001.10:g.217057482A>G
ESRRG RefSeqGene	NG_029784.1:g.258616T>C

Gene: ESRRG, estrogen related receptor gamma(minus strand)

Molecule type	Change	Amino acid[Codon]	SO Term
ESRRG transcript variant 4	NM_001134285.2:c.	N/A	Intron Variant
ESRRG transcript variant 6	NM_001243505.1:c.	N/A	Intron Variant
ESRRG transcript variant 7	NM_001243506.1:c.	N/A	Intron Variant
ESRRG transcript variant 8	NM_001243507.1:c.	N/A	Intron Variant
ESRRG transcript variant 9	NM_001243509.1:c.	N/A	Intron Variant
ESRRG transcript variant 10	NM_001243510.2:c.	N/A	Intron Variant
ESRRG transcript variant 11	NM_001243511.2:c.	N/A	Intron Variant
ESRRG transcript variant 12	NM_001243512.1:c.	N/A	Intron Variant
ESRRG transcript variant 13	NM_001243513.1:c.	N/A	Intron Variant
ESRRG transcript variant 2	NM_206594.2:c.	N/A	Intron Variant
ESRRG transcript variant 3	NM_206595.2:c.	N/A	Intron Variant
ESRRG transcript variant 14	NM_001243514.1:c.	N/A	Genic Upstream Transcript Variant
ESRRG transcript variant 15	NM_001243515.1:c.	N/A	Genic Upstream Transcript Variant
ESRRG transcript variant 16	NM_001243518.1:c.	N/A	Genic Upstream Transcript Variant
ESRRG transcript variant 17	NM_001243519.1:c.	N/A	Genic Upstream Transcript Variant
ESRRG transcript variant 1	NM_001438.3:c.	N/A	Genic Upstream Transcript Variant
ESRRG transcript variant X2	XM_011509265.2:c.	N/A	Intron Variant
ESRRG transcript variant X7	XM_011509266.2:c.	N/A	Intron Variant
ESRRG transcript variant X23	XM_011509274.1:c.	N/A	Intron Variant
ESRRG transcript variant X29	XM_011509275.1:c.	N/A	Intron Variant
ESRRG transcript variant X28	XM_011509277.1:c.	N/A	Intron Variant
ESRRG transcript variant X30	XM_011509278.1:c.	N/A	Intron Variant
ESRRG transcript variant X1	XM_017000621.1:c.	N/A	Intron Variant
ESRRG transcript variant X3	XM_017000622.1:c.	N/A	Intron Variant
ESRRG transcript variant X4	XM_017000623.1:c.	N/A	Intron Variant
ESRRG transcript variant X5	XM_017000624.1:c.	N/A	Intron Variant
ESRRG transcript variant X6	XM_017000625.1:c.	N/A	Intron Variant
ESRRG transcript variant X18	XM_017000631.1:c.	N/A	Intron Variant
ESRRG transcript variant X19	XM_017000632.1:c.	N/A	Intron Variant
ESRRG transcript variant X21	XM_017000633.1:c.	N/A	Intron Variant
ESRRG transcript variant X21	XM_017000634.1:c.	N/A	Intron Variant
ESRRG transcript variant X25	XM_017000636.1:c.	N/A	Intron Variant
ESRRG transcript variant X26	XM_017000637.1:c.	N/A	Intron Variant
ESRRG transcript variant X32	XM_017000638.1:c.	N/A	Intron Variant
ESRRG transcript variant X36	XM_017000639.1:c.	N/A	Intron Variant
ESRRG transcript variant X34	XM_017000640.1:c.	N/A	Intron Variant
ESRRG transcript variant X36	XM_017000642.1:c.	N/A	Intron Variant
ESRRG transcript variant X37	XM_017000643.1:c.	N/A	Intron Variant
ESRRG transcript variant X38	XM_017000644.1:c.	N/A	Intron Variant
ESRRG transcript variant X39	XM_017000645.1:c.	N/A	Intron Variant
ESRRG transcript variant X40	XM_017000646.1:c.	N/A	Intron Variant
ESRRG transcript variant X41	XM_017000647.1:c.	N/A	Intron Variant
ESRRG transcript variant X42	XM_017000648.1:c.	N/A	Intron Variant
ESRRG transcript variant X43	XM_017000649.1:c.	N/A	Intron Variant
ESRRG transcript variant X8	XM_011509267.1:c.	N/A	Genic Upstream Transcript Variant
ESRRG transcript variant X9	XM_011509268.2:c.	N/A	Genic Upstream Transcript Variant
ESRRG transcript variant X10	XM_011509269.2:c.	N/A	Genic Upstream Transcript Variant
ESRRG transcript variant X11	XM_011509270.1:c.	N/A	Genic Upstream Transcript Variant
ESRRG transcript variant X15	XM_011509271.2:c.	N/A	Genic Upstream Transcript Variant
ESRRG transcript variant X22	XM_011509276.1:c.	N/A	Genic Upstream Transcript Variant
ESRRG transcript variant X27	XM_011509279.1:c.	N/A	Genic Upstream Transcript Variant
ESRRG transcript variant X31	XM_011509280.2:c.	N/A	Genic Upstream Transcript Variant
ESRRG transcript variant X11	XM_017000626.1:c.	N/A	Genic Upstream Transcript Variant
ESRRG transcript variant X12	XM_017000627.1:c.	N/A	Genic Upstream Transcript Variant
ESRRG transcript variant X13	XM_017000628.1:c.	N/A	Genic Upstream Transcript Variant
ESRRG transcript variant X15	XM_017000629.1:c.	N/A	Genic Upstream Transcript Variant
ESRRG transcript variant X14	XM_017000630.1:c.	N/A	Genic Upstream Transcript Variant
ESRRG transcript variant X24	XM_017000635.1:c.	N/A	Genic Upstream Transcript Variant
ESRRG transcript variant X37	XM_017000641.1:c.	N/A	Genic Upstream Transcript Variant

Population Frequency

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	A=0.557	G=0.443
1000Genomes	American	Sub	694	A=0.740	G=0.260
1000Genomes	East Asian	Sub	1008	A=0.816	G=0.184
1000Genomes	Europe	Sub	1006	A=0.873	G=0.127
1000Genomes	Global	Study-wide	5008	A=0.752	G=0.248
1000Genomes	South Asian	Sub	978	A=0.830	G=0.170
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	A=0.884	G=0.116
The Genome Aggregation Database	African	Sub	8700	A=0.588	G=0.412
The Genome Aggregation Database	American	Sub	836	A=0.780	G=0.220
The Genome Aggregation Database	East Asian	Sub	1610	A=0.850	G=0.150
The Genome Aggregation Database	Europe	Sub	18488	A=0.885	G=0.114
The Genome Aggregation Database	Global	Study-wide	29936	A=0.793	G=0.206
The Genome Aggregation Database	Other	Sub	302	A=0.860	G=0.140
Trans-Omics for Precision Medicine	Global	Study-wide	29116	A=0.739	G=0.261
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	A=0.880	G=0.120

PMID	Title	Author	Journal
19268276	Genome-wide association study of smoking initiation and current smoking.	Vink JM	Am J Hum Genet

P-Value

SNP ID	p-value	Traits	Study
rs1436899	0.000712	nicotine smoking	19268276

eQTL of rs1436899 in Brain tissues (GTEx Analysis Release V7)

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

meQTL of rs1436899 in Fetal Brain

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr1	217100848	217100934	E068	43366
chr1	217083547	217083667	E069	26065
chr1	217029789	217029846	E070	-27636
chr1	217030086	217030136	E070	-27346
chr1	217030476	217030655	E070	-26827
chr1	217097084	217097153	E071	39602
chr1	217083547	217083667	E072	26065
chr1	217100127	217100275	E072	42645
chr1	217083547	217083667	E074	26065
chr1	217100127	217100275	E074	42645
chr1	217100335	217100810	E074	42853
chr1	217100848	217100934	E074	43366
chr1	217063648	217063803	E081	6166
chr1	217064274	217064577	E081	6792
chr1	217064632	217064687	E081	7150
chr1	217064840	217064910	E081	7358
chr1	217074179	217074403	E081	16697
chr1	217074451	217074505	E081	16969
chr1	217100127	217100275	E082	42645
chr1	217100335	217100810	E082	42853

rs1436899

Genomic Coordinates

Gene: ESRRG, estrogen related receptor gamma(minus strand)

Population Frequency

P-Value

eQTL of rs1436899 in Brain tissues (GTEx Analysis Release V7)

meQTL of rs1436899 in Fetal Brain

Genomic View

Chromatin Interaction

Enhancer Annotation (GRCh37.p13)