rs1441142

Homo sapiens
G>A
LOC105373612 : Intron Variant
LOC151121 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
A=0402 (12045/29934,GnomAD)
A=0360 (10482/29118,TOPMED)
A=0428 (2141/5008,1000G)
A=0455 (1752/3854,ALSPAC)
A=0470 (1744/3708,TWINSUK)
chr2:129245705 (GRCh38.p7) (2q21.1)
AD
GWASdb2
1   publication(s)
See rs on genome
20 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 2NC_000002.12:g.129245705G>A
GRCh37.p13 chr 2NC_000002.11:g.130003278G>A

Gene: LOC151121, uncharacterized LOC151121(minus strand)

Molecule type Change Amino acid[Codon] SO Term
LINC01854 transcript variant 1NR_122040.1:n.N/AIntron Variant
LINC01854 transcript variant 2NR_122041.1:n.N/AIntron Variant
LINC01854 transcript variant 3NR_122042.1:n.N/AIntron Variant

Gene: LOC105373612, uncharacterized LOC105373612(plus strand)

Molecule type Change Amino acid[Codon] SO Term
LOC105373612 transcriptXR_001739709.1:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.816A=0.184
1000GenomesAmericanSub694G=0.480A=0.520
1000GenomesEast AsianSub1008G=0.295A=0.705
1000GenomesEuropeSub1006G=0.568A=0.432
1000GenomesGlobalStudy-wide5008G=0.572A=0.428
1000GenomesSouth AsianSub978G=0.600A=0.400
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.545A=0.455
The Genome Aggregation DatabaseAfricanSub8714G=0.773A=0.227
The Genome Aggregation DatabaseAmericanSub832G=0.470A=0.530
The Genome Aggregation DatabaseEast AsianSub1620G=0.223A=0.777
The Genome Aggregation DatabaseEuropeSub18466G=0.552A=0.447
The Genome Aggregation DatabaseGlobalStudy-wide29934G=0.597A=0.402
The Genome Aggregation DatabaseOtherSub302G=0.620A=0.380
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.640A=0.360
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.530A=0.470
PMID Title Author Journal
24962325Genome-wide survival analysis of age at onset of alcohol dependence in extended high-risk COGA families.Kapoor MDrug Alcohol Depend

P-Value

SNP ID p-value Traits Study
rs14411426.77E-06alcohol dependence (age at onset)24962325

eQTL of rs1441142 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1441142 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr2129990903129991022E070-12256
chr2129991443129991904E070-11374
chr2129990903129991022E081-12256
chr2129991443129991904E081-11374
chr2129996773129997036E081-6242
chr2130010223130010353E0816945
chr2130010398130011293E0817120
chr2130038915130039052E08135637
chr2130039472130039687E08136194
chr2130039843130039996E08136565
chr2130050579130050658E08147301
chr2130050695130050812E08147417
chr2129996773129997036E082-6242
chr2130010223130010353E0826945
chr2130038591130038845E08235313
chr2130038915130039052E08235637
chr2130039472130039687E08236194
chr2130039843130039996E08236565
chr2130050579130050658E08247301
chr2130050695130050812E08247417