rs1449675

Homo sapiens
T>C
LOC101928923 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
C=0093 (2798/29970,GnomAD)
C=0098 (2876/29118,TOPMED)
C=0084 (423/5008,1000G)
C=0059 (228/3854,ALSPAC)
C=0058 (216/3708,TWINSUK)
chr6:156021488 (GRCh38.p7) (6q25.3)
AD
GWASdb2
1   publication(s)
See rs on genome
48 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 6NC_000006.12:g.156021488T>C
GRCh37.p13 chr 6NC_000006.11:g.156342622T>C

Gene: LOC101928923, uncharacterized LOC101928923(minus strand)

Molecule type Change Amino acid[Codon] SO Term
LOC101928923 transcriptXR_001744423.1:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.872C=0.128
1000GenomesAmericanSub694T=0.940C=0.060
1000GenomesEast AsianSub1008T=0.899C=0.101
1000GenomesEuropeSub1006T=0.925C=0.075
1000GenomesGlobalStudy-wide5008T=0.916C=0.084
1000GenomesSouth AsianSub978T=0.970C=0.030
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.941C=0.059
The Genome Aggregation DatabaseAfricanSub8722T=0.875C=0.125
The Genome Aggregation DatabaseAmericanSub838T=0.950C=0.050
The Genome Aggregation DatabaseEast AsianSub1616T=0.895C=0.105
The Genome Aggregation DatabaseEuropeSub18492T=0.920C=0.079
The Genome Aggregation DatabaseGlobalStudy-wide29970T=0.906C=0.093
The Genome Aggregation DatabaseOtherSub302T=0.910C=0.090
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.901C=0.098
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.942C=0.058
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs14496750.000194alcohol dependence20201924

eQTL of rs1449675 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1449675 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr6156296440156296829E068-45793
chr6156307533156307618E069-35004
chr6156306232156306286E070-36336
chr6156306305156306529E070-36093
chr6156306543156306686E070-35936
chr6156306735156307433E070-35189
chr6156313897156314207E070-28415
chr6156314295156314360E070-28262
chr6156314372156314477E070-28145
chr6156314480156314873E070-27749
chr6156334769156334819E070-7803
chr6156334930156335000E070-7622
chr6156348949156349098E0706327
chr6156367559156367649E07024937
chr6156368243156368293E07025621
chr6156368390156368430E07025768
chr6156368757156368891E07026135
chr6156369009156369139E07026387
chr6156369221156369275E07026599
chr6156369328156369378E07026706
chr6156369458156369508E07026836
chr6156369649156369732E07027027
chr6156391267156391436E07048645
chr6156391490156391530E07048868
chr6156391708156391748E07049086
chr6156305196156305246E081-37376
chr6156306232156306286E081-36336
chr6156306305156306529E081-36093
chr6156306543156306686E081-35936
chr6156306735156307433E081-35189
chr6156307533156307618E081-35004
chr6156307747156307874E081-34748
chr6156313737156313846E081-28776
chr6156313897156314207E081-28415
chr6156314295156314360E081-28262
chr6156314372156314477E081-28145
chr6156314480156314873E081-27749
chr6156349272156349328E0816650
chr6156366589156367384E08123967
chr6156367559156367649E08124937
chr6156306232156306286E082-36336
chr6156306305156306529E082-36093
chr6156306543156306686E082-35936
chr6156306735156307433E082-35189
chr6156307533156307618E082-35004
chr6156307747156307874E082-34748
chr6156366589156367384E08223967
chr6156369009156369139E08226387