rs1456796

Homo sapiens
A>C
LOC728755 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
C=0198 (5929/29902,GnomAD)
C=0236 (6898/29118,TOPMED)
C=0245 (1229/5008,1000G)
C=0103 (397/3854,ALSPAC)
C=0111 (413/3708,TWINSUK)
chr14:27341265 (GRCh38.p7) (14q12)
ND
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 14NC_000014.9:g.27341265A>C
GRCh37.p13 chr 14NC_000014.8:g.27810471A>C

Gene: LOC728755, uncharacterized LOC728755(minus strand)

Molecule type Change Amino acid[Codon] SO Term
LOC728755 transcript variant X1XR_943665.2:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.579C=0.421
1000GenomesAmericanSub694A=0.810C=0.190
1000GenomesEast AsianSub1008A=0.774C=0.226
1000GenomesEuropeSub1006A=0.887C=0.113
1000GenomesGlobalStudy-wide5008A=0.755C=0.245
1000GenomesSouth AsianSub978A=0.800C=0.200
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.897C=0.103
The Genome Aggregation DatabaseAfricanSub8712A=0.625C=0.375
The Genome Aggregation DatabaseAmericanSub834A=0.830C=0.170
The Genome Aggregation DatabaseEast AsianSub1602A=0.758C=0.242
The Genome Aggregation DatabaseEuropeSub18452A=0.887C=0.112
The Genome Aggregation DatabaseGlobalStudy-wide29902A=0.801C=0.198
The Genome Aggregation DatabaseOtherSub302A=0.790C=0.210
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.763C=0.236
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.889C=0.111
PMID Title Author Journal
20158304A genomewide association study of nicotine and alcohol dependence in Australian and Dutch populations.Lind PATwin Res Hum Genet

P-Value

SNP ID p-value Traits Study
rs14567966.86E-05alcohol and nictotine co-dependence20158304

eQTL of rs1456796 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1456796 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.