rs1459124

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
C==0334 (10000/29940,GnomAD)
C==0307 (8939/29118,TOPMED)
C==0254 (1272/5008,1000G)
C==0396 (1526/3854,ALSPAC)
C==0402 (1490/3708,TWINSUK)
chr14:98386551 (GRCh38.p7) (14q32.2)
AD
GWASdb2
1   publication(s)
See rs on genome
45 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 14NC_000014.9:g.98386551C>T
GRCh37.p13 chr 14NC_000014.8:g.98852888C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.174T=0.826
1000GenomesAmericanSub694C=0.270T=0.730
1000GenomesEast AsianSub1008C=0.256T=0.744
1000GenomesEuropeSub1006C=0.377T=0.623
1000GenomesGlobalStudy-wide5008C=0.254T=0.746
1000GenomesSouth AsianSub978C=0.220T=0.780
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.396T=0.604
The Genome Aggregation DatabaseAfricanSub8716C=0.224T=0.776
The Genome Aggregation DatabaseAmericanSub838C=0.340T=0.660
The Genome Aggregation DatabaseEast AsianSub1618C=0.304T=0.696
The Genome Aggregation DatabaseEuropeSub18466C=0.388T=0.611
The Genome Aggregation DatabaseGlobalStudy-wide29940C=0.334T=0.666
The Genome Aggregation DatabaseOtherSub302C=0.320T=0.680
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.307T=0.693
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.402T=0.598
PMID Title Author Journal
22072270Genome-wide association study identifies 5q21 and 9p24.1 (KDM4C) loci associated with alcohol withdrawal symptoms.Wang KSJ Neural Transm (Vienna)

P-Value

SNP ID p-value Traits Study
rs14591245.55E-05alcohol withdrawal symptoms22072270

eQTL of rs1459124 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1459124 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr149887449998874599E06821611
chr149887466698874727E06821778
chr149881404998814175E069-38713
chr149881510998815150E069-37738
chr149880766998807775E070-45113
chr149880803998808093E070-44795
chr149880826298808315E070-44573
chr149881404998814175E070-38713
chr149881440498814536E070-38352
chr149881456298814692E070-38196
chr149882970798829783E070-23105
chr149882980498829864E070-23024
chr149882999098830062E070-22826
chr149883017098830224E070-22664
chr149883121398831294E070-21594
chr149883139998831621E070-21267
chr149883174398831851E070-21037
chr149883219298832242E070-20646
chr149884052098840879E070-12009
chr149884088298841017E070-11871
chr149887132498871714E07018436
chr149887176298871822E07018874
chr149881404998814175E071-38713
chr149881440498814536E071-38352
chr149881456298814692E071-38196
chr149881563198815695E071-37193
chr149887388998873939E07121001
chr149887449998874599E07121611
chr149887466698874727E07121778
chr149881404998814175E072-38713
chr149881440498814536E072-38352
chr149881456298814692E072-38196
chr149881510998815150E072-37738
chr149881440498814536E074-38352
chr149881456298814692E074-38196
chr149881510998815150E074-37738
chr149887449998874599E07421611
chr149887466698874727E07421778
chr149880766998807775E081-45113
chr149884052098840879E081-12009
chr149884088298841017E081-11871
chr149880803998808093E082-44795
chr149881372098813771E082-39117
chr149881404998814175E082-38713
chr149884088298841017E082-11871