rs1459124

Organism: Homo sapiens

Alleles: C>T

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

C==0334 (10000/29940,GnomAD)
C==0307 (8939/29118,TOPMED)
C==0254 (1272/5008,1000G)
C==0396 (1526/3854,ALSPAC)
C==0402 (1490/3708,TWINSUK)

Position: chr14:98386551 (GRCh38.p7) (14q32.2)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 45 Enhancers around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 14	NC_000014.9:g.98386551C>T
GRCh37.p13 chr 14	NC_000014.8:g.98852888C>T

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	C=0.174	T=0.826
1000Genomes	American	Sub	694	C=0.270	T=0.730
1000Genomes	East Asian	Sub	1008	C=0.256	T=0.744
1000Genomes	Europe	Sub	1006	C=0.377	T=0.623
1000Genomes	Global	Study-wide	5008	C=0.254	T=0.746
1000Genomes	South Asian	Sub	978	C=0.220	T=0.780
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	C=0.396	T=0.604
The Genome Aggregation Database	African	Sub	8716	C=0.224	T=0.776
The Genome Aggregation Database	American	Sub	838	C=0.340	T=0.660
The Genome Aggregation Database	East Asian	Sub	1618	C=0.304	T=0.696
The Genome Aggregation Database	Europe	Sub	18466	C=0.388	T=0.611
The Genome Aggregation Database	Global	Study-wide	29940	C=0.334	T=0.666
The Genome Aggregation Database	Other	Sub	302	C=0.320	T=0.680
Trans-Omics for Precision Medicine	Global	Study-wide	29118	C=0.307	T=0.693
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	C=0.402	T=0.598

PMID	Title	Author	Journal
22072270	Genome-wide association study identifies 5q21 and 9p24.1 (KDM4C) loci associated with alcohol withdrawal symptoms.	Wang KS	J Neural Transm (Vienna)

SNP ID	p-value	Traits	Study
rs1459124	5.55E-05	alcohol withdrawal symptoms	22072270

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

There is no significant Hi-C chromatin interaction data for this SNP.

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr14	98874499	98874599	E068	21611
chr14	98874666	98874727	E068	21778
chr14	98814049	98814175	E069	-38713
chr14	98815109	98815150	E069	-37738
chr14	98807669	98807775	E070	-45113
chr14	98808039	98808093	E070	-44795
chr14	98808262	98808315	E070	-44573
chr14	98814049	98814175	E070	-38713
chr14	98814404	98814536	E070	-38352
chr14	98814562	98814692	E070	-38196
chr14	98829707	98829783	E070	-23105
chr14	98829804	98829864	E070	-23024
chr14	98829990	98830062	E070	-22826
chr14	98830170	98830224	E070	-22664
chr14	98831213	98831294	E070	-21594
chr14	98831399	98831621	E070	-21267
chr14	98831743	98831851	E070	-21037
chr14	98832192	98832242	E070	-20646
chr14	98840520	98840879	E070	-12009
chr14	98840882	98841017	E070	-11871
chr14	98871324	98871714	E070	18436
chr14	98871762	98871822	E070	18874
chr14	98814049	98814175	E071	-38713
chr14	98814404	98814536	E071	-38352
chr14	98814562	98814692	E071	-38196
chr14	98815631	98815695	E071	-37193
chr14	98873889	98873939	E071	21001
chr14	98874499	98874599	E071	21611
chr14	98874666	98874727	E071	21778
chr14	98814049	98814175	E072	-38713
chr14	98814404	98814536	E072	-38352
chr14	98814562	98814692	E072	-38196
chr14	98815109	98815150	E072	-37738
chr14	98814404	98814536	E074	-38352
chr14	98814562	98814692	E074	-38196
chr14	98815109	98815150	E074	-37738
chr14	98874499	98874599	E074	21611
chr14	98874666	98874727	E074	21778
chr14	98807669	98807775	E081	-45113
chr14	98840520	98840879	E081	-12009
chr14	98840882	98841017	E081	-11871
chr14	98808039	98808093	E082	-44795
chr14	98813720	98813771	E082	-39117
chr14	98814049	98814175	E082	-38713
chr14	98840882	98841017	E082	-11871