rs1473730

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0083 (2509/29938,GnomAD)
C=0057 (1659/29118,TOPMED)
C=0078 (391/5008,1000G)
C=0092 (355/3854,ALSPAC)
C=0099 (367/3708,TWINSUK)
chr6:16918319 (GRCh38.p7) (6p22.3)
AD
GWASdb2
1   publication(s)
See rs on genome
41 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 6NC_000006.12:g.16918319T>C
GRCh37.p13 chr 6NC_000006.11:g.16918550T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.992C=0.008
1000GenomesAmericanSub694T=0.940C=0.060
1000GenomesEast AsianSub1008T=0.809C=0.191
1000GenomesEuropeSub1006T=0.904C=0.096
1000GenomesGlobalStudy-wide5008T=0.922C=0.078
1000GenomesSouth AsianSub978T=0.950C=0.050
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.908C=0.092
The Genome Aggregation DatabaseAfricanSub8732T=0.986C=0.014
The Genome Aggregation DatabaseAmericanSub832T=0.940C=0.060
The Genome Aggregation DatabaseEast AsianSub1612T=0.824C=0.176
The Genome Aggregation DatabaseEuropeSub18460T=0.891C=0.108
The Genome Aggregation DatabaseGlobalStudy-wide29938T=0.916C=0.083
The Genome Aggregation DatabaseOtherSub302T=0.830C=0.170
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.943C=0.057
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.901C=0.099
PMID Title Author Journal
19581569Genome-wide association study of alcohol dependence.Treutlein JArch Gen Psychiatry

P-Value

SNP ID p-value Traits Study
rs14737309.91E-05alcohol dependence19581569

eQTL of rs1473730 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1473730 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr61690350816903613E067-14937
chr61690350816903613E068-14937
chr61690366616904158E068-14392
chr61696491716965605E06946367
chr61689908016899647E070-18903
chr61690208216902290E070-16260
chr61690234516902551E070-15999
chr61690282716903446E070-15104
chr61690350816903613E070-14937
chr61690366616904158E070-14392
chr61696461416964664E07246064
chr61696491716965605E07246367
chr61696491716965605E07346367
chr61696461416964664E07446064
chr61689908016899647E081-18903
chr61690208216902290E081-16260
chr61690234516902551E081-15999
chr61690282716903446E081-15104
chr61690350816903613E081-14937
chr61690366616904158E081-14392
chr61690504816905635E081-12915
chr61690571916906071E081-12479
chr61690610616906765E081-11785
chr61690682316906987E081-11563
chr61690712616907206E081-11344
chr61690730016907392E081-11158
chr61694016016940266E08121610
chr61694717216948414E08128622
chr61694846216948682E08129912
chr61694873116948900E08130181
chr61696491716965605E08146367
chr61689908016899647E082-18903
chr61690282716903446E082-15104
chr61690350816903613E082-14937
chr61690366616904158E082-14392
chr61690504816905635E082-12915
chr61690571916906071E082-12479
chr61690610616906765E082-11785
chr61692869816928940E08210148
chr61693312016933457E08214570
chr61693379416933844E08215244