SNP Detail Info-rs1474797

Organism: Homo sapiens

Alleles: A>G

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

G=0220 (6611/29950,GnomAD)
G=0206 (6005/29118,TOPMED)
G=0213 (1065/5008,1000G)
G=0234 (900/3854,ALSPAC)
G=0225 (835/3708,TWINSUK)

Position: chr1:186998061 (GRCh38.p7) (1q31.1)

Phenotype: OD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 2 Enhancers around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 1	NC_000001.11:g.186998061A>G
GRCh37.p13 chr 1	NC_000001.10:g.186967193A>G

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	A=0.825	G=0.175
1000Genomes	American	Sub	694	A=0.710	G=0.290
1000Genomes	East Asian	Sub	1008	A=0.885	G=0.115
1000Genomes	Europe	Sub	1006	A=0.798	G=0.202
1000Genomes	Global	Study-wide	5008	A=0.787	G=0.213
1000Genomes	South Asian	Sub	978	A=0.680	G=0.320
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	A=0.766	G=0.234
The Genome Aggregation Database	African	Sub	8720	A=0.822	G=0.178
The Genome Aggregation Database	American	Sub	836	A=0.690	G=0.310
The Genome Aggregation Database	East Asian	Sub	1620	A=0.856	G=0.144
The Genome Aggregation Database	Europe	Sub	18474	A=0.756	G=0.243
The Genome Aggregation Database	Global	Study-wide	29950	A=0.779	G=0.220
The Genome Aggregation Database	Other	Sub	300	A=0.810	G=0.190
Trans-Omics for Precision Medicine	Global	Study-wide	29118	A=0.793	G=0.206
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	A=0.775	G=0.225

PMID	Title	Author	Journal
23183491	Genome-wide association study identifies a potent locus associated with human opioid sensitivity.	Nishizawa D	Mol Psychiatry

SNP ID	p-value	Traits	Study
rs1474797	0.000113	Opioid sensitivity	23183491

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr1	186954824	186954967	E067	-12226
chr1	186965103	186965272	E081	-1921

rs1474797