rs1474797

Homo sapiens
A>G
None
Check p-value
SNV (Single Nucleotide Variation)
G=0220 (6611/29950,GnomAD)
G=0206 (6005/29118,TOPMED)
G=0213 (1065/5008,1000G)
G=0234 (900/3854,ALSPAC)
G=0225 (835/3708,TWINSUK)
chr1:186998061 (GRCh38.p7) (1q31.1)
OD
GWASdb2
1   publication(s)
See rs on genome
2 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 1NC_000001.11:g.186998061A>G
GRCh37.p13 chr 1NC_000001.10:g.186967193A>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.825G=0.175
1000GenomesAmericanSub694A=0.710G=0.290
1000GenomesEast AsianSub1008A=0.885G=0.115
1000GenomesEuropeSub1006A=0.798G=0.202
1000GenomesGlobalStudy-wide5008A=0.787G=0.213
1000GenomesSouth AsianSub978A=0.680G=0.320
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.766G=0.234
The Genome Aggregation DatabaseAfricanSub8720A=0.822G=0.178
The Genome Aggregation DatabaseAmericanSub836A=0.690G=0.310
The Genome Aggregation DatabaseEast AsianSub1620A=0.856G=0.144
The Genome Aggregation DatabaseEuropeSub18474A=0.756G=0.243
The Genome Aggregation DatabaseGlobalStudy-wide29950A=0.779G=0.220
The Genome Aggregation DatabaseOtherSub300A=0.810G=0.190
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.793G=0.206
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.775G=0.225
PMID Title Author Journal
23183491Genome-wide association study identifies a potent locus associated with human opioid sensitivity.Nishizawa DMol Psychiatry

P-Value

SNP ID p-value Traits Study
rs14747970.000113Opioid sensitivity23183491

eQTL of rs1474797 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1474797 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr1186954824186954967E067-12226
chr1186965103186965272E081-1921