rs1478684

Homo sapiens
T>G
None
Check p-value
SNV (Single Nucleotide Variation)
G=0242 (7250/29914,GnomAD)
G=0242 (7056/29118,TOPMED)
G=0342 (1712/5008,1000G)
G=0223 (859/3854,ALSPAC)
G=0227 (842/3708,TWINSUK)
chr11:27315798 (GRCh38.p7) (11p14.1)
OD
GWASdb2
1   publication(s)
See rs on genome
9 Enhancers around
10 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 11NC_000011.10:g.27315798T>G
GRCh37.p13 chr 11NC_000011.9:g.27337345T>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.751G=0.249
1000GenomesAmericanSub694T=0.570G=0.430
1000GenomesEast AsianSub1008T=0.566G=0.434
1000GenomesEuropeSub1006T=0.786G=0.214
1000GenomesGlobalStudy-wide5008T=0.658G=0.342
1000GenomesSouth AsianSub978T=0.560G=0.440
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.777G=0.223
The Genome Aggregation DatabaseAfricanSub8712T=0.751G=0.249
The Genome Aggregation DatabaseAmericanSub830T=0.550G=0.450
The Genome Aggregation DatabaseEast AsianSub1616T=0.556G=0.444
The Genome Aggregation DatabaseEuropeSub18454T=0.787G=0.212
The Genome Aggregation DatabaseGlobalStudy-wide29914T=0.757G=0.242
The Genome Aggregation DatabaseOtherSub302T=0.790G=0.210
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.757G=0.242
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.773G=0.227
PMID Title Author Journal
23183491Genome-wide association study identifies a potent locus associated with human opioid sensitivity.Nishizawa DMol Psychiatry

P-Value

SNP ID p-value Traits Study
rs14786845.37E-05Opioid sensitivity23183491

eQTL of rs1478684 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1478684 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr112738289827383006E06745553
chr112738312027383187E06745775
chr112738289827383006E06945553
chr112738312027383187E06945775
chr112738320527383758E07145860
chr112731508227315988E081-21357
chr112733060427331164E081-6181
chr112737280027372887E08135455
chr112738312027383187E08145775




Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr112738403927385566E06746694
chr112738403927385566E06846694
chr112738403927385566E06946694
chr112738403927385566E07046694
chr112738403927385566E07146694
chr112738403927385566E07246694
chr112738403927385566E07346694
chr112738403927385566E07446694
chr112738403927385566E08146694
chr112738403927385566E08246694