rs1485179

Homo sapiens
C>T
GRM7 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
C==0461 (13809/29914,GnomAD)
C==0459 (13389/29118,TOPMED)
C==0497 (2490/5008,1000G)
T=0458 (1765/3854,ALSPAC)
T=0451 (1674/3708,TWINSUK)
chr3:7562021 (GRCh38.p7) (3p26.1)
AD
GWASdb2
1   publication(s)
See rs on genome
36 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 3NC_000003.12:g.7562021C>T
GRCh37.p13 chr 3NC_000003.11:g.7603708C>T
GRM7 RefSeqGeneNG_029781.1:g.705907C>T

Gene: GRM7, glutamate metabotropic receptor 7(plus strand)

Molecule type Change Amino acid[Codon] SO Term
GRM7 transcript variant 1NM_000844.3:c.N/AIntron Variant
GRM7 transcript variant 2NM_181874.2:c.N/AIntron Variant
GRM7 transcript variant X5XM_017006272.1:c.N/AIntron Variant
GRM7 transcript variant X6XM_017006273.1:c.N/AIntron Variant
GRM7 transcript variant X1XR_001740134.1:n.N/AIntron Variant
GRM7 transcript variant X2XR_001740135.1:n.N/AIntron Variant
GRM7 transcript variant X3XR_001740136.1:n.N/AIntron Variant
GRM7 transcript variant X4XR_001740137.1:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.297T=0.703
1000GenomesAmericanSub694C=0.500T=0.500
1000GenomesEast AsianSub1008C=0.720T=0.280
1000GenomesEuropeSub1006C=0.531T=0.469
1000GenomesGlobalStudy-wide5008C=0.497T=0.503
1000GenomesSouth AsianSub978C=0.500T=0.500
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.542T=0.458
The Genome Aggregation DatabaseAfricanSub8706C=0.342T=0.658
The Genome Aggregation DatabaseAmericanSub832C=0.470T=0.530
The Genome Aggregation DatabaseEast AsianSub1610C=0.675T=0.325
The Genome Aggregation DatabaseEuropeSub18464C=0.496T=0.503
The Genome Aggregation DatabaseGlobalStudy-wide29914C=0.461T=0.538
The Genome Aggregation DatabaseOtherSub302C=0.620T=0.380
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.459T=0.540
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.549T=0.451
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs14851790.000673alcohol dependence21314694

eQTL of rs1485179 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1485179 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr375597297559786E067-43922
chr375598287560011E067-43697
chr375600687560173E067-43535
chr375602147560443E067-43265
chr375597297559786E068-43922
chr375598287560011E068-43697
chr375597297559786E069-43922
chr375598287560011E069-43697
chr375600687560173E069-43535
chr375597297559786E070-43922
chr375598287560011E070-43697
chr375600687560173E070-43535
chr375602147560443E070-43265
chr375833677583432E070-20276
chr375597297559786E071-43922
chr375598287560011E071-43697
chr375600687560173E071-43535
chr375602147560443E071-43265
chr375851797585273E071-18435
chr375598287560011E072-43697
chr375600687560173E072-43535
chr375597297559786E073-43922
chr375598287560011E073-43697
chr375600687560173E073-43535
chr375597297559786E081-43922
chr375598287560011E081-43697
chr375600687560173E081-43535
chr375879817588441E081-15267
chr375884797588540E081-15168
chr375902757590388E081-13320
chr376162747616492E08112566
chr375597297559786E082-43922
chr375598287560011E082-43697
chr375600687560173E082-43535
chr375833677583432E082-20276
chr375902757590388E082-13320