SNP Detail Info-rs1485179

Organism: Homo sapiens

Alleles: C>T

Gene : Feature

GRM7 : Intron Variant

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

C==0461 (13809/29914,GnomAD)
C==0459 (13389/29118,TOPMED)
C==0497 (2490/5008,1000G)
T=0458 (1765/3854,ALSPAC)
T=0451 (1674/3708,TWINSUK)

Position: chr3:7562021 (GRCh38.p7) (3p26.1)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 36 Enhancers around

Promoter: 0 Promoter around

Molecule type	Change	Amino acid[Codon]	SO Term
GRM7 transcript variant 1	NM_000844.3:c.	N/A	Intron Variant
GRM7 transcript variant 2	NM_181874.2:c.	N/A	Intron Variant
GRM7 transcript variant X5	XM_017006272.1:c.	N/A	Intron Variant
GRM7 transcript variant X6	XM_017006273.1:c.	N/A	Intron Variant
GRM7 transcript variant X1	XR_001740134.1:n.	N/A	Intron Variant
GRM7 transcript variant X2	XR_001740135.1:n.	N/A	Intron Variant
GRM7 transcript variant X3	XR_001740136.1:n.	N/A	Intron Variant
GRM7 transcript variant X4	XR_001740137.1:n.	N/A	Intron Variant

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	C=0.297	T=0.703
1000Genomes	American	Sub	694	C=0.500	T=0.500
1000Genomes	East Asian	Sub	1008	C=0.720	T=0.280
1000Genomes	Europe	Sub	1006	C=0.531	T=0.469
1000Genomes	Global	Study-wide	5008	C=0.497	T=0.503
1000Genomes	South Asian	Sub	978	C=0.500	T=0.500
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	C=0.542	T=0.458
The Genome Aggregation Database	African	Sub	8706	C=0.342	T=0.658
The Genome Aggregation Database	American	Sub	832	C=0.470	T=0.530
The Genome Aggregation Database	East Asian	Sub	1610	C=0.675	T=0.325
The Genome Aggregation Database	Europe	Sub	18464	C=0.496	T=0.503
The Genome Aggregation Database	Global	Study-wide	29914	C=0.461	T=0.538
The Genome Aggregation Database	Other	Sub	302	C=0.620	T=0.380
Trans-Omics for Precision Medicine	Global	Study-wide	29118	C=0.459	T=0.540
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	C=0.549	T=0.451

PMID	Title	Author	Journal
21314694	Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.	Kendler KS	Alcohol Clin Exp Res

SNP ID	p-value	Traits	Study
rs1485179	0.000673	alcohol dependence	21314694

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr3	7559729	7559786	E067	-43922
chr3	7559828	7560011	E067	-43697
chr3	7560068	7560173	E067	-43535
chr3	7560214	7560443	E067	-43265
chr3	7559729	7559786	E068	-43922
chr3	7559828	7560011	E068	-43697
chr3	7559729	7559786	E069	-43922
chr3	7559828	7560011	E069	-43697
chr3	7560068	7560173	E069	-43535
chr3	7559729	7559786	E070	-43922
chr3	7559828	7560011	E070	-43697
chr3	7560068	7560173	E070	-43535
chr3	7560214	7560443	E070	-43265
chr3	7583367	7583432	E070	-20276
chr3	7559729	7559786	E071	-43922
chr3	7559828	7560011	E071	-43697
chr3	7560068	7560173	E071	-43535
chr3	7560214	7560443	E071	-43265
chr3	7585179	7585273	E071	-18435
chr3	7559828	7560011	E072	-43697
chr3	7560068	7560173	E072	-43535
chr3	7559729	7559786	E073	-43922
chr3	7559828	7560011	E073	-43697
chr3	7560068	7560173	E073	-43535
chr3	7559729	7559786	E081	-43922
chr3	7559828	7560011	E081	-43697
chr3	7560068	7560173	E081	-43535
chr3	7587981	7588441	E081	-15267
chr3	7588479	7588540	E081	-15168
chr3	7590275	7590388	E081	-13320
chr3	7616274	7616492	E081	12566
chr3	7559729	7559786	E082	-43922
chr3	7559828	7560011	E082	-43697
chr3	7560068	7560173	E082	-43535
chr3	7583367	7583432	E082	-20276
chr3	7590275	7590388	E082	-13320

rs1485179