rs1489843

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0352 (10523/29894,GnomAD)
A=0331 (9665/29118,TOPMED)
A=0240 (1203/5008,1000G)
A=0444 (1710/3854,ALSPAC)
A=0453 (1680/3708,TWINSUK)
chr10:53607809 (GRCh38.p7) (10q21.1)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 10NC_000010.11:g.53607809G>A
GRCh37.p13 chr 10NC_000010.10:g.55367569G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.812A=0.188
1000GenomesAmericanSub694G=0.630A=0.370
1000GenomesEast AsianSub1008G=0.933A=0.067
1000GenomesEuropeSub1006G=0.567A=0.433
1000GenomesGlobalStudy-wide5008G=0.760A=0.240
1000GenomesSouth AsianSub978G=0.800A=0.200
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.556A=0.444
The Genome Aggregation DatabaseAfricanSub8708G=0.771A=0.229
The Genome Aggregation DatabaseAmericanSub836G=0.650A=0.350
The Genome Aggregation DatabaseEast AsianSub1614G=0.948A=0.052
The Genome Aggregation DatabaseEuropeSub18434G=0.565A=0.434
The Genome Aggregation DatabaseGlobalStudy-wide29894G=0.648A=0.352
The Genome Aggregation DatabaseOtherSub302G=0.530A=0.470
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.668A=0.331
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.547A=0.453
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs14898430.000458alcohol dependence20201924

eQTL of rs1489843 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1489843 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.