SNP Detail Info-rs1489843

Organism: Homo sapiens

Alleles: G>A

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

A=0352 (10523/29894,GnomAD)
A=0331 (9665/29118,TOPMED)
A=0240 (1203/5008,1000G)
A=0444 (1710/3854,ALSPAC)
A=0453 (1680/3708,TWINSUK)

Position: chr10:53607809 (GRCh38.p7) (10q21.1)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 0 Enhancer around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 10	NC_000010.11:g.53607809G>A
GRCh37.p13 chr 10	NC_000010.10:g.55367569G>A

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	G=0.812	A=0.188
1000Genomes	American	Sub	694	G=0.630	A=0.370
1000Genomes	East Asian	Sub	1008	G=0.933	A=0.067
1000Genomes	Europe	Sub	1006	G=0.567	A=0.433
1000Genomes	Global	Study-wide	5008	G=0.760	A=0.240
1000Genomes	South Asian	Sub	978	G=0.800	A=0.200
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	G=0.556	A=0.444
The Genome Aggregation Database	African	Sub	8708	G=0.771	A=0.229
The Genome Aggregation Database	American	Sub	836	G=0.650	A=0.350
The Genome Aggregation Database	East Asian	Sub	1614	G=0.948	A=0.052
The Genome Aggregation Database	Europe	Sub	18434	G=0.565	A=0.434
The Genome Aggregation Database	Global	Study-wide	29894	G=0.648	A=0.352
The Genome Aggregation Database	Other	Sub	302	G=0.530	A=0.470
Trans-Omics for Precision Medicine	Global	Study-wide	29118	G=0.668	A=0.331
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	G=0.547	A=0.453

PMID	Title	Author	Journal
20201924	Genome-wide association study of alcohol dependence implicates a region on chromosome 11.	Edenberg HJ	Alcohol Clin Exp Res

SNP ID	p-value	Traits	Study
rs1489843	0.000458	alcohol dependence	20201924

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

rs1489843