rs1495858

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0217 (6481/29850,GnomAD)
A=0168 (4892/29116,TOPMED)
A=0216 (1083/5008,1000G)
A=0250 (963/3854,ALSPAC)
A=0248 (920/3708,TWINSUK)
chr13:70668635 (GRCh38.p7) (13q21.33)
AD
GWASdb2
1   publication(s)
See rs on genome
1 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 13NC_000013.11:g.70668635G>A
GRCh37.p13 chr 13NC_000013.10:g.71242767G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.939A=0.061
1000GenomesAmericanSub694G=0.840A=0.160
1000GenomesEast AsianSub1008G=0.690A=0.310
1000GenomesEuropeSub1006G=0.706A=0.294
1000GenomesGlobalStudy-wide5008G=0.784A=0.216
1000GenomesSouth AsianSub978G=0.710A=0.290
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.750A=0.250
The Genome Aggregation DatabaseAfricanSub8716G=0.917A=0.083
The Genome Aggregation DatabaseAmericanSub834G=0.850A=0.150
The Genome Aggregation DatabaseEast AsianSub1598G=0.688A=0.312
The Genome Aggregation DatabaseEuropeSub18400G=0.723A=0.276
The Genome Aggregation DatabaseGlobalStudy-wide29850G=0.782A=0.217
The Genome Aggregation DatabaseOtherSub302G=0.860A=0.140
Trans-Omics for Precision MedicineGlobalStudy-wide29116G=0.832A=0.168
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.752A=0.248
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs14958580.000664alcohol dependence20201924

eQTL of rs1495858 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1495858 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr137120053071200759E082-42008