rs1499378

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0149 (4479/29874,GnomAD)
T=0150 (4386/29118,TOPMED)
T=0134 (669/5008,1000G)
T=0128 (493/3854,ALSPAC)
T=0133 (494/3708,TWINSUK)
chr14:42461113 (GRCh38.p7) (14q21.1)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 14NC_000014.9:g.42461113C>T
GRCh37.p13 chr 14NC_000014.8:g.42930316C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.779T=0.221
1000GenomesAmericanSub694C=0.940T=0.060
1000GenomesEast AsianSub1008C=0.885T=0.115
1000GenomesEuropeSub1006C=0.876T=0.124
1000GenomesGlobalStudy-wide5008C=0.866T=0.134
1000GenomesSouth AsianSub978C=0.910T=0.090
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.872T=0.128
The Genome Aggregation DatabaseAfricanSub8696C=0.786T=0.214
The Genome Aggregation DatabaseAmericanSub836C=0.930T=0.070
The Genome Aggregation DatabaseEast AsianSub1594C=0.933T=0.067
The Genome Aggregation DatabaseEuropeSub18450C=0.868T=0.131
The Genome Aggregation DatabaseGlobalStudy-wide29874C=0.850T=0.149
The Genome Aggregation DatabaseOtherSub298C=0.910T=0.090
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.849T=0.150
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.867T=0.133
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs14993780.00093alcohol dependence20201924

eQTL of rs1499378 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1499378 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.