rs1509718

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0302 (9055/29924,GnomAD)
T=0371 (10820/29118,TOPMED)
T=0306 (1534/5008,1000G)
T=0181 (696/3854,ALSPAC)
T=0184 (683/3708,TWINSUK)
chr11:109120846 (GRCh38.p7) (11q22.3)
AD
GWASdb2
1   publication(s)
See rs on genome
20 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 11NC_000011.10:g.109120846C>T
GRCh37.p13 chr 11NC_000011.9:g.108991573C>T
RNA5SP349 pseudogeneNG_033494.1:g.241G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.337T=0.663
1000GenomesAmericanSub694C=0.700T=0.300
1000GenomesEast AsianSub1008C=0.935T=0.065
1000GenomesEuropeSub1006C=0.779T=0.221
1000GenomesGlobalStudy-wide5008C=0.694T=0.306
1000GenomesSouth AsianSub978C=0.830T=0.170
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.819T=0.181
The Genome Aggregation DatabaseAfricanSub8700C=0.388T=0.612
The Genome Aggregation DatabaseAmericanSub838C=0.750T=0.250
The Genome Aggregation DatabaseEast AsianSub1620C=0.923T=0.077
The Genome Aggregation DatabaseEuropeSub18464C=0.819T=0.180
The Genome Aggregation DatabaseGlobalStudy-wide29924C=0.697T=0.302
The Genome Aggregation DatabaseOtherSub302C=0.800T=0.200
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.628T=0.371
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.816T=0.184
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs15097180.000909alcohol dependence20201924

eQTL of rs1509718 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1509718 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr11108982801108984125E070-7448
chr11108984207108984257E070-7316
chr11108984380108984430E070-7143
chr11108984586108984685E070-6888
chr11108985289108985888E070-5685
chr11108985982108986066E070-5507
chr11108992332108992570E070759
chr11109019535109019647E07427962
chr11109019677109019809E07428104
chr11108942088108942306E081-49267
chr11108942408108943081E081-48492
chr11108943156108943381E081-48192
chr11108982801108984125E081-7448
chr11108984207108984257E081-7316
chr11108984380108984430E081-7143
chr11108984586108984685E081-6888
chr11108982801108984125E082-7448
chr11108984207108984257E082-7316
chr11108984380108984430E082-7143
chr11108984586108984685E082-6888