rs1512454

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
G==0425 (12718/29870,GnomAD)
G==0406 (11822/29118,TOPMED)
G==0275 (1375/5008,1000G)
A=0495 (1909/3854,ALSPAC)
G==0497 (1844/3708,TWINSUK)
chr6:127529821 (GRCh38.p7) (6q22.33)
AD
GWASdb2
1   publication(s)
See rs on genome
54 Enhancers around
53 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 6NC_000006.12:g.127529821G>A
GRCh37.p13 chr 6NC_000006.11:g.127850966G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.343A=0.657
1000GenomesAmericanSub694G=0.270A=0.730
1000GenomesEast AsianSub1008G=0.015A=0.985
1000GenomesEuropeSub1006G=0.492A=0.508
1000GenomesGlobalStudy-wide5008G=0.275A=0.725
1000GenomesSouth AsianSub978G=0.230A=0.770
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.505A=0.495
The Genome Aggregation DatabaseAfricanSub8698G=0.375A=0.625
The Genome Aggregation DatabaseAmericanSub830G=0.260A=0.740
The Genome Aggregation DatabaseEast AsianSub1616G=0.007A=0.993
The Genome Aggregation DatabaseEuropeSub18424G=0.493A=0.506
The Genome Aggregation DatabaseGlobalStudy-wide29870G=0.425A=0.574
The Genome Aggregation DatabaseOtherSub302G=0.470A=0.530
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.406A=0.594
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.497A=0.503
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs15124540.000845alcohol dependence21314694

eQTL of rs1512454 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1512454 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr6127802845127803172E067-47794
chr6127804559127805277E067-45689
chr6127805345127805923E067-45043
chr6127805998127806048E067-44918
chr6127806057127806240E067-44726
chr6127807760127807870E067-43096
chr6127808000127808121E067-42845
chr6127809024127809132E067-41834
chr6127833783127833865E067-17101
chr6127805345127805923E068-45043
chr6127805998127806048E068-44918
chr6127806057127806240E068-44726
chr6127807760127807870E068-43096
chr6127802845127803172E069-47794
chr6127804559127805277E069-45689
chr6127807760127807870E069-43096
chr6127808000127808121E069-42845
chr6127809024127809132E069-41834
chr6127841368127841462E069-9504
chr6127809024127809132E070-41834
chr6127830866127830941E070-20025
chr6127841673127841723E070-9243
chr6127867111127867165E07016145
chr6127867436127867523E07016470
chr6127802845127803172E071-47794
chr6127805345127805923E071-45043
chr6127805998127806048E071-44918
chr6127806057127806240E071-44726
chr6127807164127807239E071-43727
chr6127807760127807870E071-43096
chr6127808000127808121E071-42845
chr6127809024127809132E071-41834
chr6127805345127805923E072-45043
chr6127805998127806048E072-44918
chr6127806057127806240E072-44726
chr6127807760127807870E072-43096
chr6127808000127808121E072-42845
chr6127809024127809132E072-41834
chr6127806057127806240E073-44726
chr6127804559127805277E074-45689
chr6127805998127806048E074-44918
chr6127806057127806240E074-44726
chr6127807760127807870E074-43096
chr6127808000127808121E074-42845
chr6127809024127809132E074-41834
chr6127804559127805277E081-45689
chr6127809024127809132E081-41834
chr6127820878127820988E081-29978
chr6127832029127832350E081-18616
chr6127833783127833865E081-17101
chr6127841368127841462E081-9504
chr6127841673127841723E081-9243
chr6127867111127867165E08116145
chr6127841673127841723E082-9243










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr6127835815127838163E067-12803
chr6127838168127838275E067-12691
chr6127838803127838857E067-12109
chr6127839253127839374E067-11592
chr6127839427127840806E067-10160
chr6127840839127841123E067-9843
chr6127841156127841214E067-9752
chr6127835815127838163E068-12803
chr6127838168127838275E068-12691
chr6127839253127839374E068-11592
chr6127839427127840806E068-10160
chr6127840839127841123E068-9843
chr6127835815127838163E069-12803
chr6127838168127838275E069-12691
chr6127839253127839374E069-11592
chr6127839427127840806E069-10160
chr6127840839127841123E069-9843
chr6127835815127838163E070-12803
chr6127838168127838275E070-12691
chr6127838803127838857E070-12109
chr6127839253127839374E070-11592
chr6127839427127840806E070-10160
chr6127840839127841123E070-9843
chr6127841156127841214E070-9752
chr6127835815127838163E071-12803
chr6127839253127839374E071-11592
chr6127839427127840806E071-10160
chr6127835815127838163E072-12803
chr6127838168127838275E072-12691
chr6127839253127839374E072-11592
chr6127839427127840806E072-10160
chr6127840839127841123E072-9843
chr6127835815127838163E073-12803
chr6127838168127838275E073-12691
chr6127839427127840806E073-10160
chr6127835815127838163E074-12803
chr6127838168127838275E074-12691
chr6127839427127840806E074-10160
chr6127840839127841123E074-9843
chr6127835815127838163E081-12803
chr6127838168127838275E081-12691
chr6127838803127838857E081-12109
chr6127839253127839374E081-11592
chr6127839427127840806E081-10160
chr6127840839127841123E081-9843
chr6127841156127841214E081-9752
chr6127835815127838163E082-12803
chr6127838168127838275E082-12691
chr6127838803127838857E082-12109
chr6127839253127839374E082-11592
chr6127839427127840806E082-10160
chr6127840839127841123E082-9843
chr6127841156127841214E082-9752